Estimating 24-hour urine sodium level with spot urine sodium and creatinine.
Estimating 24-hour urine sodium level with spot urine sodium and creatinine.
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DOI：
10.3346/jkms.2014.29.s2.s97
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发表时间：
2014-09
影响因子：
4.5
通讯作者：
Park JH
中科院分区：
文献类型：
--
作者：
Koo HS;Kim YC;Ahn SY;Oh SW;Kim S;Chin HJ;Park JH
根据点尿钠估算24小时尿钠排泄水平，并验证公式的有效性以确定低盐摄入量<100 mEq Na/天的状态。收集了 400 名患者的 24 小时尿液样本。使用三个公式估算 24 小时尿肌酐水平：新导出的韩式方程 (E24UCR_K)、田中方程 (E24UCR_T) 和 Cockcroft-Gault (E24UCR_CG) 方程。这三个方程的估计值和测量值 24 小时尿肌酐之间的相关系数分别为 0.863、0.846 和 0.896（所有 P<0.001）。估算24小时尿钠水平后，估算的24小时尿钠水平与实测的24小时尿钠水平之间的相关系数分别为0.466、0.490和0.516（均P<0.001）。三个公式使用估计量≥100 mEq/天来估计测量的24小时尿钠≥100 mEq/天的灵敏度分别为84.3%、87.6%和84.8%。总之，用于估算 24 小时尿钠含量的三个方程有助于确定低盐摄入状态。
The 24-hr urine sodium excretion level was estimated based on the spot urine sodium, and the efficacy of the formula was validated to determine the status of low salt intake <100 mEq Na/day. The 24-hr urine samples were collected from 400 patients. The 24-hr urine creatinine level was estimated with the use of three formulas: a newly derived Korean equation (E24UCR_K), and Tanaka (E24UCR_T) and Cockcroft-Gault (E24UCR_CG) equations. The correlation coefficients between the estimated and measured 24-hr urine creatinine for these three equations were 0.863, 0.846, and 0.896, respectively (All P<0.001). After estimating the 24-hr urine sodium levels, the correlation coefficients between the estimated and measured 24-hr urine sodium levels were 0.466, 0.490, and 0.516, respectively (All P<0.001). The sensitivity of three formulas to estimate the measured 24-hr urine sodium≥100 mEq/day using the estimated amount≥100 mEq/day was 84.3%, 87.6%, and 84.8%, respectively. In conclusion, the three equations used to estimate the 24-hr urine sodium content were useful to determine the status of low salt intake.