High-resolution magnetic resonance imaging of trabecular bone structure
High-resolution magnetic resonance imaging of trabecular bone structure
复制标题
DOI：
10.1007/bf03194359
复制
发表时间：
1997-01-01
影响因子：
4
通讯作者：
Majumdar, S
中科院分区：
文献类型：
--
作者：
Genant, HK;Majumdar, S
尽管骨密度（BMD）是影响骨强度和骨折风险的最重要因素之一，但研究表明，独立于骨密度的骨质量和结构的变化也会影响骨强度和骨折倾向。这些其他因素的影响可能部分解释了在骨质疏松性骨折患者和非骨质疏松性骨折患者之间观察到的骨矿物质测量重叠，而不管测量地点或技术如何。因此，除了BMD外，还有一些新的新兴技术旨在量化骨小梁结构。在对小梁骨结构进行非侵入性评估的背景下，最近的努力已经指向了成像方式的发展，如磁共振（MR）成像。核磁共振成像是一种非侵入性技术，可以提供任意平面和三维的高分辨率图像，并且可能对体外和体内各种骨骼部位的小梁网络的定量表征有用。
Although bone mineral density (BMD) is one of the most important contributing factors to bone strength and fracture risk, studies have shown that changes in bone quality and structure independent of BMD influence both bone strength and propensity to fracture. The influence of these other factors may partially explain the observed overlap in bone mineral measurements between patients with and without osteoporotic fractures, irrespective of measurement site or technique. Thus, several new emerging techniques have been aimed at quantifying trabecular bone structure in addition to BMD. It is in the context of non-invasive assessment of trabecular bone architecture that recent efforts have been directed to the development of imaging modalities such as magnetic resonance (MR) imaging. MR imaging is a non-invasive technique that provides high-resolution images in arbitrary planes, as weIl as in three dimensions, and may potentially be useful for the quantitative characterization of the trabecular network both in vitro and in vivo at various skeletal sites.