Structural Centrosomal Abnormalities Push Cells toward Invasion.
Structural Centrosomal Abnormalities Push Cells toward Invasion.
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DOI：
10.1016/j.devcel.2018.04.016
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发表时间：
2018-05
影响因子：
11.8
通讯作者：
Pedro Monteiro;S. Godinho
中科院分区：
文献类型：
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作者：
Pedro Monteiro;S. Godinho
结构性中心体畸变在癌症中已经被描述很久了，但是它们对细胞生理学和肿瘤发生的影响仍然不清楚。Ganier等人（2018）表明，中心体结构异常通过促进上皮有丝分裂细胞的出芽来促进细胞播散。
Structural centrosomal aberrations have long been described in cancer, but their impact on cell physiology and tumorigenesis remains unclear. Ganier et al. (2018) show that centrosome structural abnormalities facilitate cell dissemination by promoting budding of epithelial mitotic cells.