mTOR and the control of whole body metabolism
mTOR and the control of whole body metabolism
复制标题
DOI:
10.1016/j.ceb.2009.01.024
复制
发表时间:
2009-04-01
影响因子:
7.5
通讯作者:
Hall, Michael N.
中科院分区:
文献类型:
--
作者:
Polak, Pazit;Hall, Michael N.
Mammalian Target of Rapamycin (mTOR) is a highly conserved protein kinase that functions as part of two distinct multiprotein complexes to regulate growth and metabolism. This review describes the most important recent advances in the mTOR signaling field. In addition, we provide an overview on the functions of mTOR in different organs, with a special focus on the role of mTOR in whole body energy metabolism.