ICE - A NEW DOSAGE FORM OF AN OLD DRUG
ICE - A NEW DOSAGE FORM OF AN OLD DRUG
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DOI：
10.1126/science.249.4969.631
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发表时间：
1990-08-10
期刊：
影响因子：
56.9
通讯作者：
CHO, AK
中科院分区：
文献类型：
--
作者：
CHO, AK
Ice，被描述为20世纪90年代的毒品，是(+)甲基苯丙胺盐酸盐的纯净形式；它更危险，因为它很纯净并且可以被吸入。通过这种途径服用，该药物会产生与静脉注射相似的效果，并且比摄入的效果强烈得多。详细的作用机制与可卡因不同，但甲基苯丙胺的整体兴奋作用相似。然而，甲基苯丙胺的作用会持续数小时，而可卡因的作用会在几分钟内消失。因此，冰毒只是寻求精神刺激的人滥用的另一种药物，与可卡因一样，安非他明的强迫性滥用者会反复、持续地服用这种药物。与可卡因不同，甲基苯丙胺是一种合成化合物，是在美国的非法实验室生产的。
Ice, which has been described as the drug of the 1990s, is a pure form of (+)methamphetamine hydrochloride; it is more dangerous because of its purity and because it can be inhaled. Taken by this route, the drug causes an effect similar to that from an intravenous dose, and much more intense than that from ingestion. The detailed mechanism of action differs from that of cocaine, but the overall stimulant effect of methamphetamine is similar. Methamphetamine effects, however, persist for hours, whereas cocaine effects are over in minutes. Ice is, therefore, just another agent for abuse by those seeking psychostimulation and, as with cocaine, compulsive abusers of amphetamines consume the drug repeatedly and continuously. Unlike cocaine, methamphetamine is a synthetic compound and is manufactured in illicit laboratories within the United States.