In vitro antitumour and antibacterial studies of some Pt(IV) dithiocarbamate complexes
In vitro antitumour and antibacterial studies of some Pt(IV) dithiocarbamate complexes
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DOI：
10.1016/j.saa.2005.09.023
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发表时间：
2006-09-01
影响因子：
4.4
通讯作者：
Kaushik, N. K.
中科院分区：
文献类型：
--
作者：
Manav, N.;Mishra, A. K.;Kaushik, N. K.
合成了几种[Pt（L）（2）Cl-2]型铂（IV）配合物[其中L =吗啉二硫代氨基甲酸酯（L-1），苯胺二硫代氨基甲酸酯（L-2），N-（甲基，环己基）二硫代氨基甲酸酯（L-3）和N-（乙基，环己基）二硫代氨基甲酸酯（L-4）]。通过元素分析、摩尔电导、IR、电子光谱、H-1和C-13 NMR对配合物进行了表征。发现配体以单双齿方式起作用。还进行了循环伏安研究、抗菌和体外抗肿瘤研究。(c)2005 Elsevier B. V.保留所有权利。
A few Pt(lV) complexes of the type [Pt(L)(2)Cl-2] [where L = morpholine dithiocarbamate (L-1), aniline dithiocarbamate (L-2), N-(methyl, cyclohexyl) dithiocarbarnate (L-3) and N-(ethyl, cyclohexyl) dithiocarbarnate (L-4)] were synthesized. The complexes have been characterized by elemental analysis, molar conductance, IR, electronic, H-1 and C-13 NMR spectroscopic studies. The ligands found to act in monobasic bidentate fashion. Cyclicvoltammetric studies, antibacterial and in vitro antitumour studies were also carried out. (c) 2005 Elsevier B.V. All rights reserved.