Investigation of executive function change following anterior temporal lobectomy: selective normalization of verbal fluency.
Investigation of executive function change following anterior temporal lobectomy: selective normalization of verbal fluency.
复制标题
前颞叶切除术后执行功能变化的调查：言语流畅性的选择性正常化。
DOI：
10.1037//0894-4105.14.4.501
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Gilliam,FG
中科院分区：
文献类型：
--
作者：
Martin,RC;Sawrie,SM;Edwards,R;Roth,DL;Faught,E;Kuzniecky,RI;Morawetz,RB;Gilliam,FG
伤害皮质假说预测，前颞叶切除术（ATL）后远端颞外脑区的电生理正常化将导致执行功能的改善。本研究探讨了癫痫偏侧性和癫痫控制对执行功能变化的影响。作者对 174 名接受 ATL 的颞叶癫痫患者进行了威斯康星卡片分类测试 (WCST)、Trails B 和受控口语联想测试。无论手术部位或无癫痫发作状态如何，WCST 或 Trails B 测试均未发现显着变化。然而，无癫痫发作患者的言语流畅性显着提高。研究结果与伤害皮层假说一致，表明 ATL 后选择性执行功能得到改善。这些发现根据近期研究证明手术后海马外代谢正常化进行了讨论。（PsycINFO 数据库记录 (c) 2016 APA，保留所有权利）
The nociferous cortex hypothesis predicts that electrophysiological normalization to distal extratemporal brain regions following anterior temporal lobectomy (ATL) will result in improvements in executive functioning. The present study examined the effects of seizure laterality and seizure control on executive function change. The authors administered the Wisconsin Card Sorting Test (WCST), Trails B, and the Controlled Oral Word Association Test to 174 temporal lobe epilepsy patients who underwent ATL. No significant changes were found on the WCST or Trails B tests, regardless of surgery side or seizure-free status. However, verbal fluency significantly improved in seizure-free patients. Findings were consistent with the nociferous cortex hypothesis suggesting selective executive function improvement following ATL. These findings are discussed in terms of recent research demonstrating extrahippocampal metabolic normalization following surgery.(PsycINFO Database Record (c) 2016 APA, all rights reserved)