Gene annotation bias impedes biomedical research
Gene annotation bias impedes biomedical research
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DOI:
10.1038/s41598-018-19333-x
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发表时间:
2018-01-22
影响因子:
4.6
通讯作者:
Khatri, Purvesh
中科院分区:
文献类型:
--
作者:
Haynes, Winston A.;Tomczak, Aurelie;Khatri, Purvesh
We found tremendous inequality across gene and protein annotation resources. We observed that this bias leads biomedical researchers to focus on richly annotated genes instead of those with the strongest molecular data. We advocate that researchers reduce these biases by pursuing data-driven hypotheses.