Structural asymmetries in motor and language networks in a population of healthy preterm neonates at term equivalent age: A diffusion tensor imaging and probabilistic tractography study
Structural asymmetries in motor and language networks in a population of healthy preterm neonates at term equivalent age: A diffusion tensor imaging and probabilistic tractography study
复制标题
DOI：
10.1016/j.neuroimage.2010.02.066
复制
发表时间：
2010-06-01
期刊：
影响因子：
5.7
通讯作者：
Aeby, Alec
中科院分区：
文献类型：
--
作者：
Liu, Yan;Baleriaux, Danielle;Aeby, Alec
在这项MRI研究中，我们的目标是在健康的早产儿群体中提供新的体内运动和语言网络不对称的结构标记物。应用弥散张量成像和概率纤维束成像，我们发现，除了上纵束顶颞部的体积和微结构不对称和皮质脊髓束微结构不对称的趋势外，丘脑上辐射运动部的体积不对称和CST的体积不对称的趋势在新生期已经存在。STR的感觉部分、丘脑的前部辐射(ATR)和丘脑的后部(PTR)没有不对称，SLF的额顶部也没有不对称。这些结果表明，健康的早产儿在足月相同年龄的运动和语言网络中存在结构不对称，远远早于语言和手部偏好的发展。(C)2010 Elsevier Inc.保留所有权利。
In this MRI study, we aimed to provide new in vivo structural markers of asymmetry in motor and language networks in a population of healthy preterm neonates scanned at term equivalent age. Using diffusion tensor imaging and probabilistic tractography, we showed that, besides volume and microstructural asymmetries in the parieto-temporal part of the superior longitudinal fasciculus (SLF) and a trend towards microstructural asymmetry in the corticospinal tract (CST), volume asymmetry in the motor part of the superior thalamic radiations (STR) and a trend towards volume asymmetry in the CST are already present in the neonatal period. No asymmetry was found in the sensory part of the STR, the anterior thalamic radiations (ATR), and posterior thalamic radiations (PTR) neither in the fronto-parietal part of the SLF. These results suggest that structural asymmetries in the motor and language networks are present in healthy preterm neonates at term equivalent age, well before the development of speech and hand preference. (C) 2010 Elsevier Inc. All rights reserved.