HLA antigens and non-HLA chromosome 6 markers in Micronesians from Nauru.
HLA antigens and non-HLA chromosome 6 markers in Micronesians from Nauru.
复制标题
来自瑙鲁的密克罗尼西亚人的 HLA 抗原和非 HLA 6 号染色体标记。
DOI：
10.1111/j.1399-0039.1983.tb01165.x
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
Beauchamp,M
中科院分区：
文献类型：
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作者：
Serjeantson,SW;Kirk,RL;Ranford,P;Beauchamp,M
测定了来自瑙鲁的密克罗尼西亚人的HLA - A、B、C和DR抗原分布，以及非HLA - 6染色体标记C2、BF、C4A、C4B和GLO。遗传距离分析表明瑙鲁人和菲律宾人亲缘关系密切，而连锁不平衡值证实了瑙鲁人和美拉尼西亚人之间存在一定的祖先关系。利用瑙鲁人、菲律宾人和西班牙人的HLA基因频率，估计这些群体对今天关岛查莫罗人的比例贡献为36%西班牙人、17%菲律宾人和47%密克罗尼西亚人。
HLA‐A, B, C and DR antigen distributions, together with non‐HLA chromosome 6 markers C2, BF, C4A, C4B and GLO, were determined in Micronesians from Nauru. Genetic distance analysis showed the close affinity between Nauruans and Filipinos, while linkage disequilibrium values confirmed some ancestral relationship between Nauru and Melanesia. HLA gene frequencies in Nauruan, Filipino and Spanish populations were used to estimate the proportionate contributions of these groups to the present day Chamorros of Guam as 36% Spanish, 17% Filipino and 47% Micronesian.