Volume-selective 3D turbo spin echo imaging for vascular wall imaging and distensibility measurement
Volume-selective 3D turbo spin echo imaging for vascular wall imaging and distensibility measurement
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DOI：
10.1002/jmri.10294
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发表时间：
2003-05-01
影响因子：
4.4
通讯作者：
Firmin, DN
中科院分区：
文献类型：
--
作者：
Crowe, LA;Gatehouse, P;Firmin, DN
目的：使用体积选择性 3D 涡轮自旋回波 (TSE) 技术对颈动脉壁进行成像并测量扩张性。材料和方法：已经开发出高分辨率体积选择性 3D TSE 序列。体积选择是通过 90 度和 180 度激励的正交梯度完成的，并允许在相对较短的时间内对血管壁的 3D 体积进行成像。该技术的开发允许在心动周期的任何定义阶段进行成像，以便研究血管功能和扩张性。结果：通过使用选择性体积激励减少相位编码视场 (FOV)（k(y) 步长），扫描效率得到提高。使用与传统序列相同的扫描时间，可以获取更多的血管覆盖切片（k(z) 相位编码步骤），同时保持信噪比 (SNR) 水平。该技术的实用价值在 10 名正常受试者的颈动脉高分辨率血管扩张性测量中得到了证明。结论：体积选择性 TSE 方法已用于正常受试者的颈动脉壁成像和扩张性测量。在相同的整体扫描时间和与 2D 全 FOV 图像相当的 SNR 的情况下，实现了更大的血管覆盖范围，从而获得更多的临床诊断信息。
Purpose: To use a volume-selective 3D turbo spin echo (TSE) technique to image the carotid artery wall and measure distensibility.Materials and Methods: A high-resolution volume-selective 3D TSE sequence has been developed. Volume selection is accomplished by orthogonal gradients for the 90degrees and 180degrees excitations and allows a 3D volume of vessel wall to be imaged in a relatively short time. The technique has been developed to allow imaging at any defined phase of the cardiac cycle so that the vascular function and distensibility can be studied.Results: Scan efficiency is increased by the reduced phase encode field of view (FOV) (k(y) steps) by the use of selective volume excitation. Significantly more slices (k(z) phase encode steps) for vessel coverage can be acquired with the same scan time as that of the conventional sequence while maintaining signal-to-noise ratio (SNR) levels. The practical value of the technique was demonstrated on 10 normal subjects with high-resolution vessel distensibility measurements of the carotid arteries.Conclusion: A volume-selective TSE method has been used for carotid artery wall imaging and measurement of distensibility in normal subjects. Larger coverage of the vessel, and therefore more information for clinical diagnostics, was achieved with the same overall scan time with an SNR comparable to that of 2D full FOV images.