The German Environmental Survey 1990/92 (GerES II): Primary predictors of blood cadmium levels in adults
The German Environmental Survey 1990/92 (GerES II): Primary predictors of blood cadmium levels in adults
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DOI：
10.1080/00039890109604471
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发表时间：
2001-07-01
期刊：
影响因子：
--
通讯作者：
Seifert, B
中科院分区：
文献类型：
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作者：
Hoffmann, K;Krause, C;Seifert, B
作为1990-1992年德国具有代表性的环境调查的一部分，调查人员测定了3965名年龄在25-69岁的受试者的血液中镉的水平。在多元回归分析中，研究人员考虑了大约150个变量(即人口统计学、家庭和职业特征、环境暴露、吸烟习惯、食物消费频率和其他生活方式特征)作为潜在的预测因素。根据多元回归分析的结果，作者得出了两个略有不同的预测西德和东德人群血镉水平的模型。这两个模型都包括3个主要的血镉水平预测因子。这两个模型分别解释了西德和东德观察到的血镉水平差异的51.3%和61.2%。最重要的预测因素是吸烟习惯的具体指标，该指标是通过一个单独的数学模型确定的。该模型考虑了吸烟的影响，并考虑了血中镉的生物半衰期。
As part of the representative Environmental Survey in Germany in 1990-1992, investigators determined cadmium levels in blood provided by 3,965 subjects aged 25-69 yr. The investigators considered approximately 150 variables (i.e., demographics, household and occupational characteristics, environmental exposures, smoking habits, frequency of food consumption, and additional life-style features) as potential predictors in multivariate regression analysis. On the basis of the results of multivariate regression analysis, the authors derived 2 slightly different models for the prediction of blood cadmium levels in populations from West and East Germany. Both models included 3 primary predictors of blood cadmium levels. The 2 models explained 51.3% and 61.2% of the observed variance in blood cadmium levels in West and East Germany, respectively. The most important predictor was a specific indicator for smoking habits, which was determined from a separate mathematical model. In this model, the effect of smoking was considered, and the model accounted for the biological half-life of cadmium in blood.