SELECTION OF MATERIALS FOR VENTRICULAR ASSIST PUMP DEVELOPMENT AND FABRICATION
SELECTION OF MATERIALS FOR VENTRICULAR ASSIST PUMP DEVELOPMENT AND FABRICATION
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心室辅助泵开发和制造的材料选择
DOI：
10.1097/00002480-197700230-00034
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发表时间：
1977
期刊：
影响因子：
4.2
通讯作者：
J. Keiser
中科院分区：
文献类型：
--
作者：
M. Szycher;V. Poirier;J. Keiser
我们进行了一项研究，从 8 种精心挑选的聚合物中选择了 2 种最有前途的膀胱材料。选择用于测试的聚合物包括多种聚氨酯、聚酯树脂和可混炼聚烯烃橡胶。研究了以下材料：Adiprene LW-500、Avcothane 51、Biomer、Hexsyn、Hytrel 4055、Mobay 240313、Pell Been 2103-80 AE 和 Tecoflex HR。选择过程基于一个测试矩阵，该矩阵被分为多个分段步骤，每个步骤都是其前一个步骤的逻辑延续，并且每个步骤的技术复杂性都在增加。评估了水解稳定性、耐弯曲性、可制造性、组织相容性、血液相容性和慢性组织相容性，形成接受/拒绝标准的基础。此次搜索的结果是，有 2 种生物材料被确定为最适合用于传统植绒膀胱的材料； Biomer 和 Tecoflex HR。 Biomer 和 Tecoflex HR 膀胱均在循环模拟循环耐力测试中展现了令人印象深刻的结果，Tecoflex 膀胱迄今为止已超过 5000 万次弯曲，Biomer 膀胱（运行时间最长的膀胱）超过 1.5 亿次弯曲。测试仍在继续。
A study was undertaken to select 2 of the most promising bladder materials from a list of 8 carefully chosen polymers. The polymers chosen for testing included a wide spectrum of urethanes, as well as a polyester resin and a millable polyolefin rubber. The following materials were studied: Adiprene LW-500, Avcothane 51, Biomer, Hexsyn, Hytrel 4055, Mobay 240313, Pellethane 2103-80 AE, and Tecoflex HR. The selection process was based on a test matrix which was divided into segmented steps, each a logical sequel from its predecessor, and each of increasing technical complexity. Hydrolytic stability, flexure endurance, fabricability, tissue compatibility, hemocompatibility and chronic tissue compatibility were evaluated, forming the basis for the acceptance/rejection criteria. As a result of this search, 2 biomaterials were identified as most suitable for use in conventionally flocked bladders; Biomer and Tecoflex HR. Both Biomer and Tecoflex HR bladders have demonstrated impressive results in circulatory analog loop endurance tests, with Tecoflex bladders surpassing 50 million flexes to date, and Biomer bladders (the longest running bladders) exceeding 150 million flexes. Tests are continuing.