A Questionnaire to Assess the Relevance and Credibility of Observational Studies to Inform Health Care Decision Making: An ISPOR-AMCP-NPC Good Practice Task Force Report
A Questionnaire to Assess the Relevance and Credibility of Observational Studies to Inform Health Care Decision Making: An ISPOR-AMCP-NPC Good Practice Task Force Report
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DOI：
10.1016/j.jval.2013.12.011
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发表时间：
2014-03-01
期刊：
影响因子：
4.5
通讯作者：
Crown, William
中科院分区：
文献类型：
--
作者：
Berger, Marc L.;Martin, Bradley C.;Crown, William
通过比较用于治疗特定患者群体情况的所有相关干预措施，可以更好地了解循证卫生保健决策。正在进行观察性研究，以帮助填补证据空白。然而，由于各种因素，包括对评估和解释证据的公认原则缺乏共识，广泛采用观察性研究的证据一直受到限制。成立了两个工作队，以编制问卷，协助决策者评价观察性研究，一个工作队负责回溯性研究，另一个工作队负责前瞻性研究。其目的是促进一种结构化的方法，以减少对证据的主观解释的可能性，并推动决策的一致性。将单独开发的问卷合并成一个由33个项目组成的单一问卷。这些被分为两个领域：相关性和可信度。相关性是指调查结果在多大程度上适用于决策者感兴趣的背景，如果准确的话。可信度说明研究结果在多大程度上准确回答了研究问题。问卷为评估观察性研究应给予的置信度提供了指南，并提高了人们对评估这些研究所涉及的微妙之处的认识。
Evidence-based health care decisions are best informed by comparisons of all relevant interventions used to treat conditions in specific patient populations. Observational studies are being performed to help fill evidence gaps. Widespread adoption of evidence from observational studies, however, has been limited because of various factors, including the lack of consensus regarding accepted principles for their evaluation and interpretation. Two task forces were formed to develop questionnaires to assist decision makers in evaluating observational studies, with one Task Force addressing retrospective research and the other Task Force addressing prospective research. The intent was to promote a structured approach to reduce the potential for subjective interpretation of evidence and drive consistency in decision making. Separately developed questionnaires were combined into a single questionnaire consisting of 33 items. These were divided into two domains: relevance and credibility. Relevance addresses the extent to which findings, if accurate, apply to the setting of interest to the decision maker. Credibility addresses the extent to which the study findings accurately answer the study question. The questionnaire provides a guide for assessing the degree of confidence that should be placed from observational studies and promotes awareness of the subtleties involved in evaluating those.