Modeling psychopathology structure: a symptom-level analysis of Axis I and II disorders
Modeling psychopathology structure: a symptom-level analysis of Axis I and II disorders
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DOI：
10.1017/s0033291709990183
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发表时间：
2010-02-01
影响因子：
6.9
通讯作者：
Markon, K. E.
中科院分区：
文献类型：
--
作者：
Markon, K. E.
背景对常见精神障碍的共病模式的分析一再表明，疾病之间的关系可以从广义的上位维度来理解。然而，这些分析是基于症状水平的指标，这往往是异质性的，而不是症状，这可能是更复杂的。症状水平的探索性和验证性分析被用来探讨轴I和轴II精神病理学的联合层次组织，使用2000年英国精神病发病率调查的8405人的数据。分析表明，20个确定的精神病理学的从属维度可以组织成四个广泛的上位维度：内化，外化，思维障碍，和病理性内向。这些结果扩展现有的模型框架“向下”以及“向外”分析症状，而不是诊断，并通过整合症状轴I和II的障碍在一个共同的框架。该模型表明了层次结构在精神病理学结构中的重要性，包括精神病理学结构的可复制特征，并对理解精神障碍的性质和组织具有重要意义。
Background. Analyses of co-morbidity patterns among common mental disorders have repeatedly indicated that relationships among disorders can be understood in terms of broad superordinate dimensions. However, these analyses have been based on syndromal-level indicators, which are often heterogeneous, rather than on symptoms, which are presumably more homogeneous.Method. Symptom-level exploratory and confirmatory analyses were used to explore the joint hierarchical organization of Axis I and II psychopathology, using data on 8405 individuals from the 2000 British Psychiatric Morbidity Survey.Results. Analyses indicated that 20 identified subordinate dimensions of psychopathology could be organized into four broad superordinate dimensions: Internalizing, Externalizing, Thought Disorder, and Pathological Introversion.Conclusions. These results extend existing model frameworks 'downward' as well as 'outward" by analyzing symptoms rather than diagnoses, and by integrating symptoms from Axis I and II disorders in a common framework. This model demonstrates the importance of hierarchy in psychopathology structure, comprises replicable features of psychopathology structure, and has important implications for understanding the nature and organization of mental disorders.