Changes in mood, craving, and sleep during short-term abstinence reported by male cocaine addicts. A controlled, residential study.
Changes in mood, craving, and sleep during short-term abstinence reported by male cocaine addicts. A controlled, residential study.
复制标题
男性可卡因成瘾者报告短期戒断期间情绪、渴望和睡眠的变化。
DOI：
10.1001/archpsyc.1990.01810210069010
复制
发表时间：
1990
影响因子：
--
通讯作者：
B. S. Michaelson
中科院分区：
文献类型：
--
作者：
W. Weddington;B. S. Brown;C. Haertzen;E. Cone;E. Dax;R. Herning;B. S. Michaelson
我们检查了居住在研究机构的 12 名男性（主要是静脉注射可卡因成瘾者）在 28 天内的情绪状态、对可卡因的渴望和短期戒断期间睡眠的变化。为了进行比较，我们检查了 10 名不成瘾的对照对象。除了精神活性物质使用障碍和反社会人格障碍之外，可卡因成瘾者和对照组在人口统计学和选定的 DSM-III-R 诊断方面没有显着差异。可卡因成瘾者入院前 1 周报告的精神症状得分明显较高。入院时和短期戒酒期间记录的情绪困扰和抑郁评分显着高于对照组报告的评分。成瘾者的情绪困扰分数和对可卡因的渴望在入院时最高，并在 28 天的研究中逐渐稳定下降。除了入睡困难和起床时头脑清醒之外，各组之间的睡眠报告没有显着差异。尽管入院时和一段时间内的静息心率存在显着差异，但体重增加或血压没有显着差异。鉴于不存在典型的“戒断”模式，“短期戒断”可能是对可卡因成瘾者在受控环境中开始戒断所经历的心理和身体现象的更合适的分类。
We examined changes over 28 days in mood states, craving for cocaine, and sleep during short-term abstinence reported by 12 male, predominantly intravenous-using, cocaine-addicted subjects residing in a research facility. For comparison, we examined 10 nonaddicted control subjects. There were no significant differences between cocaine addicts and controls regarding demographics and selected DSM-III-R diagnoses other than psychoactive substance use disorder and antisocial personality disorder. There were significantly higher scores of psychiatric symptoms reported by cocaine addicts 1 week before admission. Mood-distress and depression scores recorded at admission and during short-term abstinence were significantly greater than those reported by controls. Addicts' mood-distress scores and craving for cocaine were greatest at admission and decreased gradually and steadily during the 28-day study. There were no significant differences between groups regarding reports of sleep other than difficulty falling asleep and clearheadedness on arising. Although there were significant differences in resting heart rate at admission and over time, there were no significant differences in weight gain or blood pressure. Given the absence of a classic "withdrawal" pattern, "short-term abstinence" may be a more appropriate classification of psychological and physical phenomena experienced by cocaine addicts who initiate abstinence in a controlled environment.
男性和女性可卡因滥用者的比较。
影响因子：
--
作者：
Griffin,ML;Weiss,RD;Mirin,SM;Lange,U
通讯作者：
Lange,U
适用于流动可卡因滥用者的人际心理治疗。
DOI：
10.3109/00952998509016860
发表时间：
1985
期刊：
The American journal of drug and alcohol abuse
影响因子：
--
作者：
Rounsaville,BJ;Gawin,F;Kleber,H
通讯作者：
Kleber,H