Application of bismuth-telluride thermoelectrics in driving DNA amplification and sequencing reactions
Application of bismuth-telluride thermoelectrics in driving DNA amplification and sequencing reactions
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DOI：
10.1109/ict.1996.553312
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发表时间：
1996-03
期刊：
影响因子：
--
通讯作者：
J. Hansen;M. Nussbaum
中科院分区：
文献类型：
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作者：
J. Hansen;M. Nussbaum
最近，低温热电模块在生物和医学领域出现了新的应用。为了DNA扩增的目的而热循环小生物样品的实验室仪器现在在全世界的研究实验室中很常见，并且已经开发了基于几种不同技术的仪器。市场力量正在增加，表明热电非常适合这项任务，但为了建立一个高质量的仪器，必须首先克服几个障碍。其中最主要的是需要构建针对热循环优化的模块。这里提供的数据记录了一个特别坚固的模块设计，在这种要求苛刻的应用中工作良好。
Recently, a new application for low-temperature thermoelectric modules has emerged in the fields of biology and medicine. Laboratory instruments that thermally cycle small biological samples for purposes of DNA amplification are now common in research laboratories throughout the world, and instruments based upon several different technologies have been developed. Market forces are increasing showing that thermoelectrics are very well suited to this task, but several hurdles must first be overcome in order to build a quality instrument. Chief among these is the need to build modules optimized for thermal cycling. Data are presented here to document a particularly rugged design of module that works well in this demanding application.