Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort
Introduction of complementary foods in infancy and atopic sensitization at the age of 5 years: timing and food diversity in a Finnish birth cohort
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DOI：
10.1111/all.12118
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发表时间：
2013-04-01
期刊：
影响因子：
12.4
通讯作者：
Virtanen, S. M.
中科院分区：
文献类型：
--
作者：
Nwaru, B. I.;Takkinen, H. -M.;Virtanen, S. M.
目的 研究婴儿期添加辅食的时机和多样性与 5 岁儿童特应性过敏的关系。方法 在芬兰 DIPP（1 型糖尿病预测和预防）出生队列（n=3781）中，收集 2 岁以下婴儿喂养时间的数据，并在 5 岁时测量针对四种食物和四种吸入性过敏原的血清 IgE 抗体。使用逻辑回归进行分析。结果 纯母乳喂养和完全母乳喂养的中位持续时间分别为 1.4（四分位距：0.23.5）和 7.0（4.011.0）个月。当所有食物一起研究并调整混杂因素时，母乳喂养时间短会降低对桦树过敏原过敏的风险；燕麦的介绍
Objective To study the associations between timing and diversity of introduction of complementary foods during infancy and atopic sensitization in 5-year-old children. Methods In the Finnish DIPP (Type 1 Diabetes Prediction and Prevention) birth cohort (n=3781), data on the timing of infant feeding were collected up to the age of 2years and serum IgE antibodies toward four food and four inhalant allergens measured at the age of 5years. Logistic regression was used for the analyses. Results Median duration of exclusive and total breastfeeding was 1.4 (interquartile range: 0.23.5) and 7.0 (4.011.0) months, respectively. When all the foods were studied together and adjusted for confounders, short duration of breastfeeding decreased the risk of sensitization to birch allergen; introduction of oats