Which plasma antioxidants are most related to fruit and vegetable consumption?
Which plasma antioxidants are most related to fruit and vegetable consumption?
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DOI：
10.1093/aje/154.12.1113
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发表时间：
2001-12-15
影响因子：
5
通讯作者：
Helzlsouer, K
中科院分区：
文献类型：
--
作者：
Block, G;Norkus, E;Helzlsouer, K
大量证据表明，水果和蔬菜的摄入可以降低患某些癌症和其他慢性疾病的风险。虽然含有水果和蔬菜的多样化饮食可能比任何单一营养素带来的益处更大，但掌握受水果和蔬菜摄入影响最大的血浆营养素的数据将很有用。作者通过简化的 CLUE II 食物频率问卷和几种血浆抗氧化剂测量了水果和蔬菜摄入量之间的相关性。这项研究包括 116 名年龄 35-72 岁的男性受试者，他们不吸烟也不服用维生素补充剂，并在马里兰州华盛顿县的 CLUE II 研究中提供了血液样本。测定血浆中的抗坏血酸、β-胡萝卜素、β-隐黄质以及α-和γ-生育酚。经脂质和能量调整后，抗坏血酸与水果和蔬菜摄入量的偏相关性为 r = 0.64，β-胡萝卜素为 r = 0.44，β-隐黄质为 r = 0.50。虽然这项研究没有讨论功效，但此处看到的抗坏血酸与水果和蔬菜摄入量之间的更强关联可能意味着，在许多流行病学研究中，抗坏血酸是水果和蔬菜保护作用的重要组成部分。
Substantial evidence suggests that fruit and vegetable intake reduces the risk of some cancers and other chronic diseases. While a varied diet containing fruits and vegetables may confer benefits greater than those of any single nutrient, it would be useful to have data on the plasma nutrients most influenced by fruit and vegetable intake. The authors examined the correlation between fruit and vegetable intake as measured by the abbreviated CLUE II food frequency questionnaire and several plasma antioxidants. This study includes 116 male subjects aged 35-72 years who were nonsmokers and nonusers of vitamin supplements and who provided blood samples in the CLUE II Study in Washington County, Maryland. Plasma was assayed for ascorbic acid, betacarotene, beta-cryptoxanthin, and alpha- and gamma-tocopherol. Lipid- and energy-adjusted partial correlation for the relation with fruit and vegetable intake was r = 0.64 for ascorbic acid, r = 0.44 for beta-carotene, and r = 0.50 for beta-cryptoxanthin. While this study does not address efficacy, the stronger association of ascorbic acid with fruit and vegetable intake seen here may imply that ascorbic acid is an important component of the protective effect seen for fruits and vegetables in numerous epidemiologic studies.