Insect resistance to Bt crops:: evidence versus theory
Insect resistance to Bt crops:: evidence versus theory
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DOI：
10.1038/nbt1382
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发表时间：
2008-02-01
影响因子：
46.9
通讯作者：
Carriere, Yves
中科院分区：
文献类型：
--
作者：
Tabashnik, Bruce E.;Gassmann, Aaron J.;Carriere, Yves
昆虫抗性的进化威胁着转基因作物的持续成功，转基因作物产生杀死害虫的苏云金芽孢杆菌（Bt）毒素。最广泛用于延缓昆虫对Bt作物抗性的方法是避难所策略，该策略要求在Bt作物附近没有Bt毒素的宿主植物避难所，以促进易感害虫的存活。然而，对避难所战略的大规模测试一直存在问题。对十多年全球监测数据的分析表明，在玉米实夜蛾的一些田间种群中，抗性等位基因的频率大幅增加，但在澳大利亚、中国、西班牙和美国的其他五种主要害虫中却没有增加。H.在转基因棉花中，Bt毒素Cry1Ac没有引起大面积的作物歉收，部分原因是其他策略加强了对这种害虫的控制。监测数据记录的实地结果与避难所战略的理论相一致，表明避难所有助于延迟抵抗。
Evolution of insect resistance threatens the continued success of transgenic crops producing Bacillus thuringiensis (Bt) toxins that kill pests. The approach used most widely to delay insect resistance to Bt crops is the refuge strategy, which requires refuges of host plants without Bt toxins near Bt crops to promote survival of susceptible pests. However, large-scale tests of the refuge strategy have been problematic. Analysis of more than a decade of global monitoring data reveals that the frequency of resistance alleles has increased substantially in some field populations of Helicoverpa zea, but not in five other major pests in Australia, China, Spain and the United States. The resistance of H. zea to Bt toxin Cry1Ac in transgenic cotton has not caused widespread crop failures, in part because other tactics augment control of this pest. The field outcomes documented with monitoring data are consistent with the theory underlying the refuge strategy, suggesting that refuges have helped to delay resistance.