Patterns of change in nonverbal cognition in adolescents with Down syndrome

Patterns of change in nonverbal cognition in adolescents with Down syndrome
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DOI:
10.1016/j.ridd.2014.07.014
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发表时间:
2014-11-01
影响因子:
3.1
通讯作者:
Abbeduto, Leonard
Abbeduto, Leonard
中科院分区:
医学2区
文献类型:
--
作者:
Channell, Marie Moore;Thurman, Angela John;Abbeduto, Leonard

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本研究旨在检查 20 名患有唐氏综合症 (DS) 的男性在整个青春期非语言认知能力的纵向变化。我们使用分层线性模型来检查四个年度时间点 Leiter-R Brief IQ 子测试的表现变化率,并确定母亲智商与表现水平和变化率之间的关系。结果表明,样本中的智商(标准分数)没有随年龄发生显着变化,这表明 DS 患者在青春期的智商稳定,尽管一些参与者在 Leiter-R 标准分数上的表现处于最低水平,限制了解释。然而,成长分数提供了绝对能力水平的衡量标准,允许检查所有参与者的 Leiter-R 表现变化,并最大限度地减少底线效应。生长评分分析结果表明,随着时间的推移,患有 DS 的青少年的绝对非语言认知能力水平(生长评分值)显着增加,尽管生长情况因子领域而异。母亲智商并不能解释我们的 DS 青少年样本中认知表现的变异性或认知表现随时间的变化。 (C) 2014 Elsevier Ltd. 保留所有权利。
This study was designed to examine longitudinal change in nonverbal cognitive abilities across adolescence for 20 males with Down syndrome (DS). We used hierarchical linear modeling to examine the rate of change in performance on the subtests of the Leiter-R Brief IQ across four annual time points and to determine the relation between maternal IQ and level and rate of change in performance. Results indicated no significant change in IQ (standard scores) with age in the sample, suggesting IQ stability during adolescence for individuals with DS, although several participants performed at floor level on the standard scores for the Leiter-R, limiting interpretation. Growth scores, however, provide a metric of absolute ability level, allow for the examination of change in Leiter-R performance in all participants, and minimize floor effects. Results from the analysis of growth scores indicated significant gain in absolute nonverbal cognitive ability levels (growth score values) over time for the adolescents with DS, although the growth varied by subdomain. Maternal IQ did not explain variability in cognitive performance or change in that performance over time in our sample of adolescents with DS. (C) 2014 Elsevier Ltd. All rights reserved.