A convenient aminolysis of esters catalyzed by 1,5,7triazabicyclo[4.4.0]dec-5-ene (TBD) under solvent-free conditions

A convenient aminolysis of esters catalyzed by 1,5,7triazabicyclo[4.4.0]dec-5-ene (TBD) under solvent-free conditions
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DOI：
10.1016/j.tetlet.2007.03.146
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发表时间：
2007-05-28
期刊：
TETRAHEDRON LETTERS
影响因子：
1.8
通讯作者：
Mioskowski, Charles
Mioskowski, Charles
中科院分区：
化学4区
文献类型：
--
作者：
Sabot, Cyrille;Kumar, Kanduluru Ananda;Mioskowski, Charles

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Aminolysis of esters by using the organocatalyst 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) is reported. Secondary and tertiary amides were synthesized from alkyl or aryl esters with a variety of primary and secondary amines in good to excellent yields (60-94%) under solvent-free conditions (SFC). (C) 2007 Elsevier Ltd. All rights reserved.