Early predictors of treatment outcome in a partial hospital program for adolescent anorexia nervosa

Early predictors of treatment outcome in a partial hospital program for adolescent anorexia nervosa
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DOI:
10.1002/eat.23343
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发表时间:
2020-07-14
影响因子:
5.5
通讯作者:
Kaye, Walter H.
Kaye, Walter H.
中科院分区:
医学2区
文献类型:
--
作者:
Brown, Tiffany A.;Murray, Stuart B.;Kaye, Walter H.

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目的以往的研究支持进食障碍(艾德)治疗中早期症状改变的相关性;然而,很少有研究将早期体重改变与艾德精神病理学的早期改变区分开来,尤其是在更高水平的护理中。因此,本研究旨在探讨是否早期体重变化和艾德精神病理学预测青少年神经性厌食症(AN)在部分住院治疗计划的结果。方法对99例AN青少年在入院时、治疗后1个月、出院时和6个月随访时进行评估。结果入院时预期体重百分比(%EBW)越高,%EBW的早期变化越大,治疗持续时间越长,病程越短,发病年龄越早,出院时%EBW的变化越大,但随访时变化不明显。入院时更大的艾德精神病理学和更大的艾德精神病理学早期变化预测出院时艾德症状的后期变化,但不是随访。无论是早期变化的%EBW或艾德精神病理学预测缓解出院和随访的可能性。讨论结果支持早期变化在预测相同艾德结局变量的后期变化中的重要性,并表明青少年的%EBW和艾德精神病理学的早期变化可能是未来研究的重要领域。
Objective Previous research supports the relevance of early symptom change in eating disorder (ED) treatment; however, few studies have distinguished early weight change from early change in ED psychopathology, particularly in higher levels of care. Thus, the present study examined whether early change in weight and ED psychopathology predicted outcome for adolescents with anorexia nervosa (AN) in a partial hospitalization program. Method Adolescents with AN (n= 99) completed assessments at admission, 1-month after treatment admission, discharge, and 6-month follow-up. Results Higher admission percent expected body weight (%EBW), greater early change in %EBW, longer duration of treatment, shorter length of illness, and earlier age of onset predicted greater change in %EBW at discharge, but not follow-up. Greater ED psychopathology at admission and greater early change in ED psychopathology predicted later change in ED symptoms at discharge, but not follow-up. Neither early change in %EBW nor ED psychopathology predicted likelihood of remission at discharge and follow-up. Discussion Results support the importance of early change in predicting later change in the same ED outcome variables and suggest that early change in both %EBW and ED psychopathology in adolescents may be an important area for future research.