Potential assays for sperm capacitation in mammals.

Potential assays for sperm capacitation in mammals.
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哺乳动物精子获能的潜在测定。

DOI:
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发表时间:
1994
影响因子:
--
通讯作者:
M. Eisenbach
M. Eisenbach
中科院分区:
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文献类型:
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作者:
A. Cohen;M. Eisenbach

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精子获能是受精过程中的一个重要过程。它显然涉及大量的过程,其中的共同点是,它们为精子提供了进行顶体反应的潜力,即释放蛋白质水解酶,使精子能够穿透卵子的外壳。虽然人们知道能性现象已有40多年了,但人们对它的理解还远远不够,因此,迄今为止还没有对它的可操作性定义。缺乏鉴定有能力精子的化验既是这种情况的原因,也是结果。在这里,我们批判性地回顾了精子获能过程中被认为发生的主要变化,并评估了它们作为鉴定获能精子的标记物的潜在用途。
Sperm capacitation is an essential process in fertilization. It apparently involves a large number of processes, the common denominator of which is that they donate to sperm the potential to undergo the acrosome reaction, i.e., to release proteolytic enzymes enabling sperm penetration through the egg coat. Although the phenomenon of capacitation has been known for more than 40 years, it is far from understood, and, consequently, there is, as yet, no operational definition of it. The lack of an assay to identify capacitated spermatozoa is both the cause and the effect of this situation. Here we critically review the major changes that are thought to occur during sperm capacitation, and assess their potential use as markers for the identification of capacitated spermatozoa.
DOI: 10.1095/biolreprod37.5.1097
发表时间: 1987-12-01
影响因子: 3.6
作者:
CORONEL, CE;LARDY, HA
通讯作者: LARDY, HA
人类精子体外受精潜力与头部特异性甘露糖配体受体的差异表达相关。
DOI: --
发表时间: 1993
影响因子: 6.7
作者:
Benoff,S;Cooper,GW;Hurley,I;Napolitano,B;Rosenfeld,DL;Scholl,GM;Hershlag,A
通讯作者: Hershlag,A
小鼠精子与透明带结合的冷不稳定性。
DOI: 10.1002/jez.1402190204
发表时间: 1982
期刊: The Journal of experimental zoology
影响因子: --
作者:
Heffner,LJ;Storey,BT
通讯作者: Storey,BT