General Stress Responses in the Honey Bee.
General Stress Responses in the Honey Bee.
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DOI：
10.3390/insects3041271
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发表时间：
2012-12-11
期刊：
影响因子：
3
通讯作者：
Barron AB
中科院分区：
文献类型：
--
作者：
Even N;Devaud JM;Barron AB
压力的生物学概念起源于哺乳动物，其中“一般适应综合征”描述了一组对不同有害物质的共同综合生理反应。哺乳动物应激的生理机制已通过各种行为和生理研究得到广泛研究。应激反应途径的主要元素之一是内分泌下丘脑-垂体-肾上腺（HPA）轴，它是通过儿茶酚胺和皮质激素的激素级联的“战斗或逃跑”反应的基础。最近在昆虫中研究了对压力的生理反应：它们涉及生物胺（章鱼胺，多巴胺），神经肽（allatostatin，corazonin）和代谢激素（脂肪运动激素，利尿激素）。在这里，我们回顾的生理应激反应的元素，或可能是特定的蜜蜂，考虑到这个物种的经济和生态影响。这篇评论提出了一个假设的综合蜜蜂压力途径有点类似于哺乳动物HPA，涉及大脑，特别是，神经血管器官语料库cardiaca和外周目标，包括能量储存器官（脂肪体和作物）。我们讨论了这个系统如何组织代谢活动和唤醒的快速协调变化，以应对不利的环境刺激。我们强调了蜜蜂特有的一般应激反应的生理要素，以及我们缺乏信息的领域，以刺激更多的研究这种迷人而重要的昆虫如何应对压力。
The biological concept of stress originated in mammals, where a “General Adaptation Syndrome” describes a set of common integrated physiological responses to diverse noxious agents. Physiological mechanisms of stress in mammals have been extensively investigated through diverse behavioral and physiological studies. One of the main elements of the stress response pathway is the endocrine hypothalamo-pituitary-adrenal (HPA) axis, which underlies the “fight-or-flight” response via a hormonal cascade of catecholamines and corticoid hormones. Physiological responses to stress have been studied more recently in insects: they involve biogenic amines (octopamine, dopamine), neuropeptides (allatostatin, corazonin) and metabolic hormones (adipokinetic hormone, diuretic hormone). Here, we review elements of the physiological stress response that are or may be specific to honey bees, given the economical and ecological impact of this species. This review proposes a hypothetical integrated honey bee stress pathway somewhat analogous to the mammalian HPA, involving the brain and, particularly, the neurohemal organ corpora cardiaca and peripheral targets, including energy storage organs (fat body and crop). We discuss how this system can organize rapid coordinated changes in metabolic activity and arousal, in response to adverse environmental stimuli. We highlight physiological elements of the general stress responses that are specific to honey bees, and the areas in which we lack information to stimulate more research into how this fascinating and vital insect responds to stress.