Assessment of Neutrophil/Lymphocyte Ratio in Patients with Age-related Macular Degeneration
Assessment of Neutrophil/Lymphocyte Ratio in Patients with Age-related Macular Degeneration
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DOI：
10.3109/09273948.2014.921715
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发表时间：
2015-01-01
影响因子：
3.3
通讯作者：
Keskin, Ugurcan
中科院分区：
文献类型：
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作者：
Ilhan, Nilufer;Daglioglu, Mutlu Cihan;Keskin, Ugurcan
目的：目的：探讨中性粒细胞/淋巴细胞比值（NLR）在老年性黄斑变性（AMD）患者炎症反应中的作用。该研究包括81名干性AMD患者（第1组），84名湿性AMD患者（第2组）和80名年龄和性别匹配的健康对照（第3组）。结果：第1组与第2组（p = 0.017）、第2组与第3组（p = 0.001）、第3组与第4组（p = 0.001）、第4组与第5组（p = 0.001）、第5组与第6组（p = 0.001）、第6组与第7组（p = 0.001）、第7组与第8组（p = 0.001）、第8组与第9组（p = 0.001）、第10组与第10组（p = 0.01）
Purpose: To investigate the neutrophil/lymphocyte ratio (NLR) as an indicator of inflammation in patients with age-related macular degeneration (AMD).Methods: Patients were evaluated by a review of records. The study included 81 patients with dry AMD (group 1), 84 patients with wet AMD (group 2), and 80 healthy age-and sex-matched controls (group 3). The NLR of the patients was obtained from the hospital laboratory archive and was measured by dividing the neutrophil count by the lymphocyte count.Results: A significant difference was found in NLR values between groups 1 and 2 (p = 0.017), groups 2 and 3 (p