Dynamic contrast enhanced MRI of the axilla in women with breast cancer: comparison with pathology of excised nodes
Dynamic contrast enhanced MRI of the axilla in women with breast cancer: comparison with pathology of excised nodes
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DOI：
10.1259/bjr.75.891.750220
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发表时间：
2002-03-01
影响因子：
2.6
通讯作者：
Payne, S
中科院分区：
文献类型：
--
作者：
Murray, AD;Staff, RT;Payne, S
腋窝淋巴结状态是乳腺癌患者最重要的预后因素，目前通过手术切除来确定。本研究旨在评估动态钆喷酸二葡胺 (Gd) 增强 MRI 是否是腋窝无创分期的准确方法。 47 名患有新发原发性乳腺癌的女性在术前接受了同侧腋窝的动态 Gd 增强 MRI。使用感兴趣区域方法对淋巴结增强进行定量分析。使用受试者工作特征（ROC）曲线方法将增强指数和淋巴结面积与切除淋巴结的组织病理学进行比较。 10例患者病理发现腋窝转移，淋巴结均≥1个，强化指数>21%，淋巴结面积>0.4 cm(2)。 37例患者腋窝淋巴结病理学阴性。其中 20 个具有增强指数
Axillary lymph node status is the most important prognostic factor in breast cancer patients and is currently determined by surgical dissection. This study was performed to assess whether dynamic gadopentetate dimeglumine (Gd) enhanced MRI is an accurate method for noninvasive staging of the axilla. 47 women with a new primary breast cancer underwent preoperative dynamic Gd enhanced MRI of the ipsilateral axilla. Lymph node enhancement was quantitatively analysed using a region of interest method. Enhancement indices and nodal area were compared with histopathology of excised nodes using a receiver operating characteristic (ROC) curve approach. 10 patients had axillary metastases pathologically and all had greater than or equal to 1 lymph node with an enhancement index of >21% and a nodal area of >0.4 cm(2). 37 patients had negative axillary nodes pathologically. 20 of these had enhancement indices