Protein structure in context: the molecular landscape of angiogenesis.

Protein structure in context: the molecular landscape of angiogenesis.
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上下文中的蛋白质结构:血管生成的分子景观。

DOI:
10.1002/bmb.20706
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发表时间:
2013
期刊:
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
影响因子:
--
通讯作者:
Sem,DanielS
Sem,DanielS
中科院分区:
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文献类型:
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作者:
Span,EliseA;Goodsell,DavidS;Ramchandran,Ramani;Franzen,MargaretA;Herman,Tim;Sem,DanielS

文献摘要

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一个由学生、教育工作者和研究人员组成的团队开发了新的材料来教授细胞环境中的细胞信号。采用两种非传统的方式:物理模型,探索在血管生成信号级联反应中的几种蛋白质的原子细节,以及蛋白质在其细胞环境中的插图,以直观地了解途径的细胞背景。该团队的经验强调了使用这些类型的材料作为培养学生对分子世界的理解和用于定义它的科学方法的有效模式。© 2013由国际生物化学和分子生物学联合会,41(4):213-223,2013
A team of students, educators, and researchers has developed new materials to teach cell signaling within its cellular context. Two nontraditional modalities are employed: physical models, to explore the atomic details of several of the proteins in the angiogenesis signaling cascade, and illustrations of the proteins in their cellular environment, to give an intuitive understanding of the cellular context of the pathway. The experiences of the team underscore the use of these types of materials as an effective mode for fostering students' understanding of the molecular world and the scientific method used to define it. © 2013 by The International Union of Biochemistry and Molecular Biology, 41(4):213–223, 2013