Facial axis angle as a risk factor for obstructive sleep apnea
Facial axis angle as a risk factor for obstructive sleep apnea
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DOI：
10.2169/internalmedicine.44.805
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发表时间：
2005-08-01
影响因子：
1.2
通讯作者：
Gejyo, F
中科院分区：
文献类型：
--
作者：
Kubota, Y;Nakayama, H;Gejyo, F
目的日本阻塞性睡眠呼吸暂停（OSA）患者的肥胖程度低于白种人，尽管他们的OSA严重程度相似，这表明他们的OSA病因可能不同。本研究的目的是确定骨因素与OSA在日本population.Methods的临床记录的研究对象进行了回顾性分析，头影测量的基础上Sella-Nasion参考和里基茨的方法进行了统计学比较Patients 206个连续的日本男性抱怨习惯性打鼾和白天嗜睡被纳入本研究。结果多元回归分析显示，体质量指数（p < 0.0001）和面轴角（p=0.007）是影响呼吸暂停低通气指数的主要因素。非肥胖、重度OSA患者的鞍-鼻根-棘下角（SNA）和鞍-鼻根-颏上角（SNB）均低于非肥胖、轻度和中度OSA患者（p值分别为0.0047和0.0016）。此外，较小的SNA和SNB似乎与非肥胖患者的OSA严重程度相关。
Objective Many Japanese patients with obstructive sleep apnea (OSA) are less obese than Caucasian OSA patients despite their similar severity of OSA, suggesting that their etiology of OSA may differ. The purpose of this study was to identify bony factors associated with OSA in the Japanese population.Methods The clinical records of study subjects were retrospectively reviewed, and cephalometric measurements based on Sella-Nasion references and the Ricketts method were statistically compared.Patients Two hundred and six consecutive Japanese men complaining of habitual snoring and daytime sleepiness were enrolled in the study. All subsequently underwent an overnight polysomnographic examination.Results Multiple regression analysis showed that the body mass index (p < 0.0001) and facial axis angle (p=0.007) were the dominant overall determinants for the apnea hypopnea index. The sella to nasion to subspinale angle (SNA) and sella to nasion to supramentale angle (SNB) were lower in the non-obese, severe group than for non-obese, mild and moderate patients with OSA (p=0.0047 and 0.0016, respectively).Conclusion The risk factors for OSA in Japanese men may be obesity and the dolico facial pattern seen by the Ricketts method. In addition, a smaller SNA and SNB seem to be associated with the severity of OSA in nonobese patients.