Schedule shifts, life quality and quantity--modeled by murine blood pressure elevation and arthropod life span.

Schedule shifts, life quality and quantity--modeled by murine blood pressure elevation and arthropod life span.
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日程安排变化、生活质量和数量——以小鼠血压升高和节肢动物寿命为模型。

DOI:
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发表时间:
1979
期刊:
International journal of chronobiology
影响因子:
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通讯作者:
Bartter Fc
Bartter Fc
中科院分区:
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文献类型:
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作者:
J. Halberg;E. Halberg;Hayes Dk;Smith Rd;F. Halberg;Delea Cs;Danielson Rs;Bartter Fc

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在50至100天及更长时间的跨度内,雄性易卒中的冈本大鼠的收缩压测量值超过200 mm Hg。在收缩压平均值出现如此显著升高的过程中,这种间歇处理的雄性冈本大鼠表现出具有统计学显著性的大幅度昼夜节律。该振幅可能至少部分代表对间歇性处理的反应;它比同龄自发性中高血压(但不容易卒中)雌性动物的振幅大数倍。
During the span from 50 to 100 days and beyond, the male stroke-prone Okamoto rat develops systolic blood pressure measures in excess of 200 mm Hg. In the course of developing such a marked elevation in systolic blood pressure mean, this intermittently handled male Okamoto rat exhibits a statistically significant circadian rhythm with large amplitude. This amplitude may represent, at least in part, a response to intermittent handling; it is several times larger than the amplitude for spontaneously mesor-hypertensive (but not stroke-prone) female animals of the same age.