Left ventricular longitudinal Systolic dysfunction is an independent marker of cardiovascular risk in patients with hypertension
Left ventricular longitudinal Systolic dysfunction is an independent marker of cardiovascular risk in patients with hypertension
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DOI：
10.1038/ajh.2008.244
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发表时间：
2008-09-01
影响因子：
3.2
通讯作者：
Mondillo, Sergio
中科院分区：
文献类型：
--
作者：
Ballo, Piercarlo;Barone, Daniele;Mondillo, Sergio
目的探讨高血压患者左室纵向收缩功能障碍的预后价值。方法应用超声心动图测量156例高血压患者的M型左房室平面位移（AVPD）和组织多普勒（TD）二尖瓣环收缩期峰值速度（%），评价左室纵向收缩功能。随访患者发生以下心血管事件：需要住院治疗的充血性心力衰竭、新发心绞痛、非致命性心肌梗死、冠状动脉血运重建术、短暂性脑缺血发作、非致命性卒中和心血管死亡。两个纵向收缩指数均可预测结局（风险比：AVPD，0.24，P < 0.001; S-m，0.22; P < 0.001）。AVPD
BACKGROUNDTo explore the prognostic value of left ventricular (LV) longitudinal systolic dysfunction in patients with hypertension.METHODSIn 156 hypertensive subjects, LV longitudinal systolic function was assessed by echocardiographic measurement of M-mode left atrioventricular plane displacement (AVPD) and Tissue Doppler (TD)-derived mitral annulus peak systolic velocity %). Patients were followed for development of the following cardiovascular events: congestive heart failure requiring hospitalization, new-onset angina, nonfatal myocardial infarction, coronary revascularization procedures, transient ischemic attack, nonfatal stroke, and cardiovascular death.RESULTSOver a follow-up of 23.3 +/- 5.4 months, 24 patients had 29 events. Both longitudinal systolic indices were predictive of outcome (hazard ratios: AVPD, 0.24, P < 0.001; S-m, 0.22; P < 0.001). AVPD