QT interval dispersion in healthy subject and survivors at sudden cardiac death: Circadian variation in a twenty-four-hour assessment

QT interval dispersion in healthy subject and survivors at sudden cardiac death: Circadian variation in a twenty-four-hour assessment
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DOI:
10.1016/s0002-9149(97)00080-5
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发表时间:
1997-05-01
影响因子:
2.8
通讯作者:
Somberg, JC
Somberg, JC
中科院分区:
医学3区
文献类型:
--
作者:
Molnar, J;Rosenthal, JE;Somberg, JC

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在20例心脏性猝死(SCD)幸存者、20例健康受试者和14例年龄、性别、诊断和治疗与14例SCD患者匹配的无心脏骤停史的对照患者中,评价了24小时从Halter采集的QT离散度(QTd)和QTd的昼夜变化。对24小时霍尔特记录进行计算机辅助QT测量;将每个记录分为288个5分钟片段,并生成代表平均QT的模板。QTd计算为Halter上每个模板的V-1和V-5导联QT间期之间的差异。SCD患者的24小时平均QTd(40 ± 28 ms)显著大于健康受试者(20 ± 10 ms)和对照患者(15 ± 5 ms)(p
Twenty-four-hour acquisition of QT dispersion (QTd) from the Halter and the circadian variation of QTd were evaluated in 20 survivors of sudden cardiac death (SCD), in 20 healthy subjects, and in 14 control patients without a history of cardiac arrest who were age, sex, diagnosis and therapy matched to 14 SCD patients. Computer-assisted QT measurements were performed on 24-hour Holter recordings; each recording was divided into 288 5-minute segments and templates representing the average QRST were generated. QTd was calculated as the difference between QT intervals in leads V-1 and V-5 for each template on Halter. The 24-hour mean QTd was significantly greater in SCD patients (40 +/- 28 ms) than in healthy subjects (20 +/- 10 ms) and control patients (15 +/- 5 ms) (p