Salivary gland adenocarcinomas: a clinicopathologic analysis of three distinctive types.
Salivary gland adenocarcinomas: a clinicopathologic analysis of three distinctive types.
复制标题
唾液腺腺癌：三种不同类型的临床病理学分析。
DOI：
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发表时间：
1987
影响因子：
2.3
通讯作者：
M. E. Tortoledo
中科院分区：
文献类型：
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作者：
Mario A. Luna;John G. Batsakis;Nelson G. Ordóñez;B. Mackay;M. E. Tortoledo
肌上皮细胞在腺癌的组织发生中起重要作用，腺癌起源于最接近腺泡的涎腺导管单位。起源于闰管的原型腺癌是终末导管癌和上皮细胞癌，两者都是典型的低度恶性肿瘤。发生于较大的无闰排泄管的涎腺腺癌，其成分中不含肌上皮细胞。一个主要的例子是涎腺导管癌，这是一种高度恶性肿瘤。这些腺癌具有独特的临床和病理特征，应被病理学家所识别。由于终末导管癌和涎腺导管癌在诊断时可能会混淆，因此应进一步确认两者，例如增加高或低级别。
Myoepithelial cells play an important role in the histogenesis of adenocarcinomas arising from the salivary duct unit nearest the acini. Prototype adenocarcinomas arising from the intercalated duct are the terminal duct carcinoma and the epimyoepithelial carcinoma, both typically low-grade malignancies. Those salivary adenocarcinomas arising from the larger nonintercalated excretory ducts do not manifest myoepithelial cells in their composition. A prime example is the salivary duct carcinoma, which is a high-grade malignancy. These adenocarcinomas have distinctive clinical and pathologic features and they should be recognized by the examining pathologist. Because of the potential clinical confusion between terminal duct carcinoma and salivary duct carcinoma when rendered as a diagnosis, each should be further qualified, eg, by adding high or low grade.