Early social communication in infants with fragile X syndrome and infant siblings of children with autism spectrum disorder
Early social communication in infants with fragile X syndrome and infant siblings of children with autism spectrum disorder
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DOI：
10.1016/j.ridd.2017.10.004
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发表时间：
2017-12-01
影响因子：
3.1
通讯作者：
Roberts, Jane B.
中科院分区：
文献类型：
--
作者：
Hahn, Laura J.;Brady, Nancy C.;Roberts, Jane B.
目的：比较脆性X综合征(FXS)婴儿、患有自闭症谱系障碍(ASIB)的婴儿兄弟姐妹和典型发育期(TD)婴儿的早期社会交流。方法和程序：参与者包括18名FXS婴儿、21名ASIBs婴儿和22名TD婴儿，年龄在7.5-14.5个月。在执行孤独症观察量表的过程中，使用沟通复杂性量表对社会沟通进行编码。结果与结果：三组之间呈现不同的描述性模式。总体而言，在控制非语言认知能力时，FXS婴儿的社交能力低于ASIB或TD婴儿。然而，在躲猫猫期间，患有FXS的婴儿与ASIB或TD婴儿的社交沟通水平相似。ASIBs组与TD组间无明显差异。对于所有婴儿来说，较高的社交沟通与较低的ASD风险相关。结论和启示：研究结果为FXS患者社交沟通的发展过程提供了洞察力。社交游戏的动态特性可能有助于刺激患有FXS的婴儿的交流。具有很强社会成分的语言干预可能对促进FXS的语言发展特别有效。
Background: Little research in fragile X syndrome (FXS) has prospectively examined early social communication.Aims: To compare early social communication in infants with FXS, infant siblings of children with autism spectrum disorder (ASIBs), and typically developing (TD) infants.Methods and procedures: Participants were 18 infants with FXS, 21 ASIBs, and 22 TD infants between 7.5-14.5 months. Social communication was coded using the Communication Complexity Scale during the administration of Autism Observation Scale for Infants.Outcomes and results: Descriptively different patterns were seen across the three groups. Overall infants with FXS had lower social communication than ASIBs or TD infants when controlling for nonverbal cognitive abilities. However, infants with FXS had similar levels of social communication as ASIBs or TD infants during peek-a-boo. No differences were observed between ASIBs and TD infants. For all infants, higher social communication was related to lower ASD risk.Conclusions and implications: Findings provide insight into the developmental course of social communication in FXS. The dynamic nature of social games may help to stimulate communication in infants with FXS. Language interventions with a strong social component may be particularly effective for promoting language development in FXS.