Radiographical and histological characteristics of submerged and non-submerged titanium implants - An experimental study in the Labrador dog
Radiographical and histological characteristics of submerged and non-submerged titanium implants - An experimental study in the Labrador dog
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DOI：
10.1034/j.1600-0501.1996.070103.x
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发表时间：
1996-03-01
影响因子：
4.3
通讯作者：
Glantz, PO
中科院分区：
文献类型：
--
作者：
Ericsson, I;Nilner, K;Glantz, PO
使用5只拉布拉多犬，在使用一步外科手术安装Branemark（R）种植体后，分析种植体周围组织的某些特征。6个钛种植体，每个下颌象限3个，安装在右侧和左侧第一磨牙和第四和第三前磨牙的区域。在右下颌象限中，采用传统的2步手术，而在左象限中，进行1步手术。在6个月期间监测动物。愈合的种植体周围粘膜活检显示浅表炎症迹象。组织学分析显示，i）连接上皮侧面的结缔组织显示出有限的炎症细胞（PICT）积聚，ii）在暴露于口腔6个月的种植体部位（1步种植体），面向基台-固定装置连接处（AFJ）的组织中始终存在炎症细胞浸润（基台ICT）。该浸润与骨嵴之间被0.8 mm宽的正常结缔组织区隔开。无论采用何种外科手术，放射学和组织学测量结果显示：i）牙槽嵴骨丢失约为2.4 mm，ii）种植体周围粘膜的高度为3.5 mm至3.9 mm，iii）骨嵴位于AFJ顶端1.1-1.5 mm以及结合上皮顶端末端（aJE），和iv）2.1- 2.4mm的接合上皮面向植入物表面。总之，本研究表明，使用犬模型，根据1步或2步手术程序安装的钛牙科种植体和Brandum Modum Branemark将获得相似的软组织适应性和适当的骨锚定（骨整合）。然而，需要进一步的研究来确定一步法的长期临床可行性。
Using 5 Labrador dogs, certain characteristics of the peri-implant tissues were analyzed after using a 1-step surgical procedure for installation of Branemark(R) implants. Six titanium implants, 3 in each mandibular quadrant, were installed in the regions of the right and left first molars and the fourth and third premolars. In the right mandibular quadrant, a traditional 2-step procedure was employed, whilst in the left quadrant, a 1-step procedure was carried out. The animals were monitored during a 6-month period. Biopsies of the healed peri-implant mucosa showed signs of superficial inflammation. The histological analysis revealed that i) the connective tissue lateral to the junctional epithelium showed limited accumulations of inflammatory cells (PICT), and ii) that at implant sites that had been exposed to the oral cavity for 6 months (1-step implants), an inflammatory cell infiltrate (abutment ICT) consistently was present in the tissues facing the abutment-fixture junction (AFJ). This infiltrate was separated from the bone crest by a 0.8-mm-wide zone of normal connective tissue. Irrespective of the surgical procedure applied, the radiographic and histometric measurements disclosed that i) the crestal bone loss was about 2.4 mm, ii) the height of the peri-implant mucosa varied from 3.5 mm to 3.9 mm, iii) the bone crest was located 1.1-1.5 mm apical of AFJ as well as of the apical termination of the junctional epithelium (aJE), and iv) a junctional epithelium of 2.1-2.4 mm faced the implant surface. In conclusion, this study demonstrates that, using a dog model, titanium dental implants ad modum Branemark installed according to a 1-step or to a 2-step surgical procedure will obtain similar soft tissue adaptation and proper bone anchorage (osseointegration). Further studies are, however, required to ascertain the long-term clinical feasibility of the 1-step approach.