PREVALENCE OF THYROID AUTOANTIBODIES IS NOT INCREASED IN BLOOD-DONORS WITH HEPATITIS-C VIRUS-INFECTION

PREVALENCE OF THYROID AUTOANTIBODIES IS NOT INCREASED IN BLOOD-DONORS WITH HEPATITIS-C VIRUS-INFECTION
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DOI:
10.1016/0168-8278(95)80216-9
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发表时间:
1995-06-01
影响因子:
25.7
通讯作者:
VILARDELL, F
VILARDELL, F
中科院分区:
医学1区
文献类型:
--
作者:
BOADAS, J;RODRIGUEZESPINOSA, J;VILARDELL, F

文献摘要

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Serum autoimmune reactions are found in many patients with hepatitis C. A high prevalence of thyroid dysfunction and antithyroid antibodies in patients with chronic hepatitis C was recently reported, We have compared the prevalence of thyroid dysfunction and antithyroid peroxidase antibodies in blood donors with hepatitis C virus (HCV) infection (study group) and in seronegative anti-HCV donors (control group), One hundred and ninety-two blood donors were studied: 96 were anti-HCV positive by ELISA 2 (48 males and 48 females; age 48+/-12.9 years, mean +/-SD), and 96 were HCV seronegative (55 males and 41 females; age 37+/-14.8 years), In all patients, serum TSH (0.25-4.2 mU/l) and fT4 (9-23 pmol/l) were measured by immunochemiluminiscent assays and antithyroid peroxidase antibodies (normal