Development of a superior frontal-intraparietal network for visuo-spatial working memory
Development of a superior frontal-intraparietal network for visuo-spatial working memory
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DOI：
10.1016/j.neuropsychologia.2005.11.019
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发表时间：
2006-01-01
期刊：
影响因子：
2.6
通讯作者：
Klingberg, Torkel
中科院分区：
文献类型：
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作者：
Klingberg, Torkel
工作记忆能力在整个童年和青春期都会增加，这对包括复杂推理在内的广泛认知能力的发展非常重要。空间广度任务是被试对空间工作记忆发展的一个敏感的测量任务，在该任务中，被试保持了关于多个物体的顺序和位置的信息。这篇评论认为，从以前的神经影像学研究的结果，调查这种发展的神经相关。年龄较大的儿童和青少年，具有较高的能力，已经发现有较高的大脑活动在顶内皮层和上级额沟的后部，在工作记忆任务的性能。白色物质的结构成熟已被研究的扩散张量磁共振成像（DTI）。这揭示了额叶中的几个区域，其中白色物质的成熟与工作记忆的发展相关。其中有一个上级额顶叶白色区，靠近与工作记忆发展有关的灰质区。此外，白色物质的成熟程度与额叶和顶叶区域的皮质激活程度呈正相关。这表明，在儿童和青少年时期，与特定认知功能相关的网络发展，例如视觉空间工作记忆。这些网络不仅包括皮层区域，还包括连接它们的白色物质束。对于视觉空间工作记忆，这个网络可能由上级额叶皮层和顶叶内皮层组成。(c)2005爱思唯尔有限公司保留所有权利。
Working memory capacity increases throughout childhood and adolescence, which is important for the development of a wide range of cognitive abilities, including complex reasoning. The spatial-span task, in which subjects retain information about the order and position of a number of objects, is a sensitive task to measure development of spatial working memory. This review considers results from previous neuroimaging studies investigating the neural correlates of this development. Older children and adolescents, with higher capacity, have been found to have higher brain activity in the intraparietal cortex and in the posterior part of the superior frontal sulcus, during the performance of working memory tasks. The structural maturation of white matter has been investigated by diffusion tensor magnetic resonance imaging (DTI). This has revealed several regions in the frontal lobes in which white matter maturation is correlated with the development of working memory. Among these is a superior fronto-parietal white matter region, located close to the grey matter regions that are implicated in the development of working memory. Furthermore, the degree of white matter maturation is positively correlated with the degree of cortical activation in the frontal and parietal regions. This suggests that during childhood and adolescence, there is development of networks related to specific cognitive functions, such as visuo-spatial working memory. These networks not only consist of cortical areas but also the white matter tracts connecting them. For visuo-spatial working memory, this network could consist of the superior frontal and intraparietal cortex. (c) 2005 Elsevier Ltd. All rights reserved.