Bacterial metabolism of thiamine. II. The isolation and characterization of 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methylthiazole-5-acetic acid (thiamine acetic acid) as an intermediate in the oxidation of thiamine.

Bacterial metabolism of thiamine. II. The isolation and characterization of 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methylthiazole-5-acetic acid (thiamine acetic acid) as an intermediate in the oxidation of thiamine.
复制标题

硫胺素的细菌代谢。

DOI:
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发表时间:
1969
期刊:
The Journal of biological chemistry
影响因子:
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通讯作者:
R. A. Neal
R. A. Neal
中科院分区:
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文献类型:
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作者:
R. A. Neal

文献摘要

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摘要化合物3-(2 ′-甲基-4 ′-氨基-5 ′-嘧啶甲基)-4-甲基噻唑-5-乙酸(硫胺乙酸)已被鉴定为土壤微生物代谢硫胺的中间体。有证据表明,化合物2-氧-3-(2 '-甲基-4'-氨基-5 '-嘧啶甲基)-4-甲基噻唑-5-乙酸(2-氧硫胺乙酸)也是该微生物代谢硫胺素的中间体。
Abstract The compound 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methylthiazole-5-acetic acid (thiamine acetic acid) has been identified as an intermediate in the metabolism of thiamine by a soil microorganism. Evidence is presented which indicates the compound 2-oxy-3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methylthiazole-5-acetic acid (2-oxythiamine acetic acid) is also an intermediate in the metabolism of thiamine by this microorganism.