Advancing Pharmacogenomics as a Component of Precision Medicine: How, Where, and Who?

Advancing Pharmacogenomics as a Component of Precision Medicine: How, Where, and Who?
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DOI:
10.1002/cpt.273
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发表时间:
2016-02
影响因子:
6.7
通讯作者:
Weitzel KW
Weitzel KW
中科院分区:
医学2区
文献类型:
--
作者:
Johnson JA;Weitzel KW

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药物基因组学是精准医学的重要组成部分。药物基因组学的实施取得了进展,但仍然存在重大障碍,包括证据、报销和临床医生知识等。广泛采用药物基因组学需要克服这些障碍,需要一个临床医生冠军群体,我们建议这个群体将是药剂师,以及一个容易进入的环境,可能是社区药房。无论走哪条路,都必须是以证据为导向的,药物基因组学必须改善与药物相关的结果,才能成为护理的标准。
Pharmacogenomics is an important element of precision medicine. Advances in pharmacogenomics implementation have been made but significant barriers remain, including evidence, reimbursement, and clinician knowledge, among others. Widespread adoption of pharmacogenomics requires overcoming these barriers, a clinician champion group, which we propose will be pharmacists, and an easily accessible setting, which may be the community pharmacy. Whatever the path, it must be evidence‐driven and pharmacogenomics must improve drug‐related outcomes to become a standard of care.