VISUAL MOTION DIRECTION IS REPRESENTED IN POPULATION-LEVEL NEURAL RESPONSE AS MEASURED BY MAGNETOENCEPHALOGRAPHY
VISUAL MOTION DIRECTION IS REPRESENTED IN POPULATION-LEVEL NEURAL RESPONSE AS MEASURED BY MAGNETOENCEPHALOGRAPHY
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DOI：
10.1016/j.neuroscience.2009.02.081
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发表时间：
2009-05-19
期刊：
影响因子：
3.3
通讯作者：
Kakigi, R.
中科院分区：
文献类型：
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作者：
Kaneoke, Y.;Urakawa, T.;Kakigi, R.
我们研究了通过脑磁图测量的视觉运动刺激引起的群体水平神经反应是否代表了方向信息。使用随机点运动学呈现不同速度、不同方向和不同相干水平的相干运动。正如之前报道的那样，对运动开始的反应的峰值潜伏期与所有方向的速度成反比，但方向对潜伏期变化没有显着影响。使用四向响应数据计算的互信息熵 (IE) 在 41.3% 的响应数据运动开始后显着增加 (>2.14)，并且最大 IE 分布在峰值响应延迟后约 20 ms。当分析在三个波形参数（峰值幅度、峰值潜伏期和 75% 波形宽度）与刺激方向的分布上显示出显着差异（通过多变量判别分析）的响应波形时，使用这些参数正确估计了 87 个波形刺激方向（80.6%）。正确估计率不受刺激速度的影响，但受相干性水平的影响，尽管速度和相干性对反应幅度的影响相似。我们的结果表明，刺激运动的速度和方向以响应波形的不同属性表示，这表明人脑至少部分地分别处理速度和方向。 (C) 2009 国际广播组织。由爱思唯尔有限公司出版。保留所有权利。
We investigated whether direction information is represented in the population-level neural response evoked by the visual motion stimulus, as measured by magnetoencephalography. Coherent motions with varied speed, varied direction, and different coherence level were presented using random dot kinematography. Peak latency of responses to motion onset was inversely related to speed in all directions, as previously reported, but no significant effect of direction on latency changes was identified. Mutual information entropy (IE) calculated using four-direction response data increased significantly (>2.14) after motion onset in 41.3% of response data and maximum IE was distributed at approximately 20 ms after peak response latency. When response waveforms showing significant differences (by multivariate discriminant analysis) in distribution of the three waveform parameters (peak amplitude, peak latency, and 75% waveform width) with stimulus directions were analyzed, 87 waveform stimulus directions (80.6%) were correctly estimated using these parameters. Correct estimation rate was unaffected by stimulus speed, but was affected by coherence level, even though both speed and coherence affected response amplitude similarly. Our results indicate that speed and direction of stimulus motion are represented in the distinct properties of a response waveform, suggesting that the human brain processes speed and direction separately, at least in part. (C) 2009 IBRO. Published by Elsevier Ltd. All rights reserved.