The complexation of rhodium(III) with acyclic diaminedithioether (DADTE) ligands.
The complexation of rhodium(III) with acyclic diaminedithioether (DADTE) ligands.
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铑(III) 与无环二胺二硫醚(DADTE) 配体的络合。
DOI：
10.1039/c0dt00813c
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Lever,SusanZemyan
中科院分区：
文献类型：
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作者：
Akgun,Zeynep;Engelbrecht,Hendrik;Fan,Kuo-Hsien;Barnes,CharlesLeslie;Cutler,CathySue;Jurisson,SilviaSabine;Lever,SusanZemyan
合成并表征了7个非环状四齿N_2S_2配体（1个二胺二硫醇和6个二胺二硫醚配体）的~（103）Rh（III）配合物。配体的结构变化包括配位原子之间的碳骨架长度（222; 232; 323; 333），是否存在与硫α位的偕二甲基基团，以及硫上有机部分的性质（氢，对甲氧基苄基和甲基）。对于每种配体，评估顺式和/或反式二氯异构体络合物的形成。两个配合物已通过单晶X-射线衍射进一步表征。进行了103铑（III）配合物的制备，并测量了总放射化学产率、体外稳定性和log D7.4值。从这些研究中，与232链长的配体，偕二甲基基团和甲基硫醚（L4）成为一个优选的配体形成铑配合物的反式几何和最高的放射化学产率。
103Rhodium(III) complexes derived from seven acyclic tetradentate N2S2 ligands (one diaminedithiol and six diaminedithioether ligands) have been synthesized and characterized. Structural variations in the ligand include the length of carbon backbone between the coordinating atoms (222; 232; 323; 333), the presence or absence of gem-dimethyl groups α to sulfur, and the nature of the organic moiety on the sulfurs (hydrogen, p-methoxybenzyl and methyl). For each ligand, the formation of cis and/or trans dichloro isomeric complexes was assessed. Two complexes have been further characterized by single crystal X-ray diffraction. Preparation of the 103Rhodium(III) complexes was conducted and overall radiochemical yields, in vitro stability and log D7.4 values were measured. From these studies, the ligand with the 232 chain length, gem-dimethyl groups and the methyl thioether (L4) emerged as a preferred ligand for formation of rhodium complexes with trans geometry and highest radiochemical yields.