HIV seroprevalence in street youth, St Petersburg, Russia
HIV seroprevalence in street youth, St Petersburg, Russia
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DOI：
10.1097/qad.0b013e3282f125b3
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发表时间：
2007-11-12
期刊：
影响因子：
3.8
通讯作者：
Hillis, Susan
中科院分区：
文献类型：
--
作者：
Kissin, Dmitry M.;Zapata, Lauren;Hillis, Susan
背景：俄罗斯街头青年中艾滋病毒感染的可靠数据是不可获得的。本研究的目的是评估圣彼得堡街头青年的艾滋病毒血清患病率，并描述与艾滋病毒感染相关的社会、性和行为特征。方法：2006年1月至5月期间进行的横断面评估包括全市41个街头青年地点的测绘，随机选择22个地点，对这些地点所有同意的15-19岁男性和女性街头青年进行快速艾滋病毒检测，以及访谈者管理的调查。校正优势比（AOR）使用逻辑回归计算，考虑到集群内的同质性。结果：在313名参与者中，117人（37.4%，95%可信区间26.1-50.2%）感染了HIV。血清患病率最高的亚群包括双重孤儿（64.3%）、无家可归者（68.1%）、以前被诊断为性传播感染者（STI; 70.5%）、目前共用针头者（86.4%）以及目前使用吸入剂（60.5%）或注射药物（78.6%），包括施托尔（82.3%）或海洛因（78.1%）的人。与HIV感染独立相关的特征包括注射毒品（AOR为23.0）、共用针头（AOR为13.3）、双孤儿或单孤儿（AOR为3.3和1.8）、无家可归（AOR为2.4）和被诊断为性传播感染（AOR为2.1）。大多数感染艾滋病毒的街头青年性行为活跃（96.6%），有多个性伴侣（65.0%），使用避孕套不一致（80.3%）。讨论：俄罗斯圣彼得堡15-19岁的街头青年有非常高的艾滋病毒血清患病率。在注射毒品的街头青年中，艾滋病毒血清感染率是东欧有史以来最高的，也是世界上最高的。(c) 2007年威科集团健康公司。
Background: Reliable data on HIV infection among Russian street youth are unavailable. The purpose of this study was to assess HIV seroprevalence among street youth in St Petersburg and to describe social, sexual, and behavioral characteristics associated with HIV infection.Methods: A cross-sectional assessment conducted during January-May 2006 included city-wide mapping of 41 street youth locations, random selection of 22 sites, rapid HIV testing for all consenting 15-19-year-old male and female street youth at these sites, and an interviewer-administered survey. Adjusted odds ratios (AOR) were calculated using logistic regression, accounting for intracluster homogeneity.Results: Of 313 participants, 117 (37.4%, 95% confidence interval 26.1-50.2%) were HIV infected. Subgroups with the highest seroprevalences included double orphans (64.3%), those with no place to live (68.1 %), those previously diagnosed with a sexually transmitted infection (STI; 70.5%), those currently sharing needles (86.4%), and those currently using inhalants (60.5%) or injection drugs (78.6%), including Stadol (82.3%) or heroin (78.1%). Characteristics independently associated with HIV infection included injecting drugs (AOR 23.0), sharing needles (AOR 13.3), being a double or single orphan (AOR 3.3 and 1.8), having no place to live (AOR 2.4), and being diagnosed with a STI (AOR 2.1). Most HIV-infected street youth were sexually active (96.6%), had multiple partners (65.0%), and used condoms inconsistently (80.3%).Discussion: Street youth aged 15-19 years in St Petersburg, Russia, have an extraordinarily high HIV seroprevalence. In street youth who are injection drug users, HIV seroprevalence is the highest ever reported for eastern Europe and is among the highest in the world. (c) 2007 Wolters Kluwer Health.