Visual area V5/hMT+ contributes to perception of tactile motion direction: a TMS study.
Visual area V5/hMT+ contributes to perception of tactile motion direction: a TMS study.
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视觉区域V5/HMT+有助于感知触觉运动方向：TMS研究。
DOI：
10.1038/srep40937
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发表时间：
2017-01-20
影响因子：
4.6
通讯作者：
Haggard P
中科院分区：
文献类型：
--
作者：
Amemiya T;Beck B;Walsh V;Gomi H;Haggard P
人类成像研究报道了与视觉运动区域V5/HMT+，原发性体感皮层（SI）和后顶叶皮层（PPC; Brodmann区域7/40）中的触觉运动感知相关的激活。但是，这样的研究无法确定这些领域是否有因果关系参与触觉运动感知。我们在整个指尖移动单个触觉点时交付了双脉冲经颅磁刺激（TMS），并使用信号检测理论来量化对运动方向的感知敏感性。 SI和V5/HMT+的TMS，但不是PPC位点，大大降低了触觉方向的区分。我们的结果表明，V5/HMT+在触觉方向处理中起因果作用，并加强了V5/HMT+服务多模式运动感知的情况。此外，我们的发现与皮质触觉处理的串行模型一致，在该模型中，高阶感知处理取决于从SI收到的信息。相比之下，我们的结果没有提供明确的证据，表明我们针对的PPC站点（Brodmann地区7/40）有助于触觉方向感知。
Human imaging studies have reported activations associated with tactile motion perception in visual motion area V5/hMT+, primary somatosensory cortex (SI) and posterior parietal cortex (PPC; Brodmann areas 7/40). However, such studies cannot establish whether these areas are causally involved in tactile motion perception. We delivered double-pulse transcranial magnetic stimulation (TMS) while moving a single tactile point across the fingertip, and used signal detection theory to quantify perceptual sensitivity to motion direction. TMS over both SI and V5/hMT+, but not the PPC site, significantly reduced tactile direction discrimination. Our results show that V5/hMT+ plays a causal role in tactile direction processing, and strengthen the case for V5/hMT+ serving multimodal motion perception. Further, our findings are consistent with a serial model of cortical tactile processing, in which higher-order perceptual processing depends upon information received from SI. By contrast, our results do not provide clear evidence that the PPC site we targeted (Brodmann areas 7/40) contributes to tactile direction perception.