A review on Sero diversity and antimicrobial resistance patterns of Shigella species in Africa, Asia and South America, 2001-2014.
A review on Sero diversity and antimicrobial resistance patterns of Shigella species in Africa, Asia and South America, 2001-2014.
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DOI：
10.1186/s13104-016-2236-7
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发表时间：
2016-08-30
影响因子：
1.8
通讯作者：
Muthupandian, Saravanan
中科院分区：
文献类型：
--
作者：
Kahsay, Atsebaha Gebrekidan;Muthupandian, Saravanan
背景：志贺氏菌，革兰氏阴性菌，是志贺氏菌病/细菌性痢疾的罪魁祸首。这是一个全球关注的问题，尽管它在发展中国家占主导地位。它们是痢疾志贺氏菌、福氏志贺氏菌、博地志贺氏菌和索尼志贺氏菌。志贺氏菌的耐药性是世界上另一个令人头痛的问题。因此;本研究旨在回顾志贺氏菌血清群在非洲、亚洲和南美洲的分布及其抗微生物模式。方法：检索2001年1月至2014年12月发表的文献。已发表的研究通过MEDLINE/Index Medicus Database、PubMed、Project Management Consultant、谷歌Scholar、Science Direct、BioMed Central和Index Copernicus进行初步搜索。结果：福氏志贺氏菌主要从4个非洲国家的7项研究和5个亚洲国家的8项研究中分离出来。进行合格研究的国家是非洲的埃塞俄比亚、肯尼亚、厄立特里亚和加纳以及亚洲的巴基斯坦、伊朗、中国、尼泊尔和印度。sonnei主要是从非洲的一项研究、亚洲的四项研究和南美洲的两项研究中分离出来的。进行合格研究的国家是非洲的埃塞俄比亚、亚洲的泰国、越南和伊朗、智利和南美洲的特立尼达。在埃及的一项合格研究和尼泊尔的一项合格研究中也报告了沙门氏菌痢疾。在任何一项符合条件的研究中，波氏弧菌的患病率都不是最高的。对来自非洲的3项研究、来自亚洲的5项研究和来自南美洲的1项研究进行了志贺氏菌血清群抗菌素耐药模式的审查。在所有地区，氨苄西林对几乎所有志贺氏菌血清群均产生高度耐药，而所有菌株对环丙沙星均敏感。结论：所选3个地区志贺氏菌血清群发病率不同。虽然sonnei在南美洲占主导地位，但在非洲和亚洲占主导地位的是flexneri。在发展中国家，志贺氏菌血清群正在对常用的抗微生物药物产生耐药性。
BACKGROUND: Shigella, gram negative bacterium, is responsible for Shigellosis/bacillary dysentery. It is a global concern although it predominates in developing countries. These are Shigella dysenteriae, Shigella flexneri, Shigella boydii and Shigella sonnei. Drug resistance by Shigella species is another headache of the world. Therefore; this study aimed to review distribution of Shigella Serogroups and their antimicrobial patterns carried out in Africa, Asia and South America.METHODS: A literature search was performed to identify published studies between January 2001 and December 2014. Published studies were identified using an initial search of the MEDLINE/Index Medicus Database, PubMed, Project Management Consultant, Google Scholar, Science Direct, BioMed Central and Index Copernicus.RESULTS: Shigella flexneri was isolated predominately from seven studies in four African countries and eight studies in five Asian countries. The countries in which eligible studies carried out were Ethiopia, Kenya, Eritrea and Ghana in Africa and Pakistan, Iran, China, Nepal and India in Asia. S. sonnei was isolated predominately from one study in Africa, four in Asia and two South America. The countries in which eligible studies carried out were Ethiopia from Africa, Thailand, Vietnam and Iran from Asia and Chile and Trinidad from South America. S. dysentery was also reported majorly from one eligible study in Egypt and one in Nepal. S. boydii did not score highest prevalence in any one of the eligible studies. Three studies from Africa, five from Asia and one from South America were reviewed for antimicrobial resistance patterns of Shigella Serogroups. In all the regions, Ampicillin developed highly resistance to almost all the Serogroups of Shigella whereas all the strains were sensitive to Ciprofloxacin.CONCLUSION: The incidence of Shigella Serogroups in the selected three regions is different. The domination of S. flexneri is observed in Africa and Asia although S. sonnei in South America is dominant. Shigella Serogroups are becoming resistance to the commonly prescribed antimicrobial drugs in developing countries.