Intraocular pressure over the clinical range of blood pressure: Blue Mountains Eye Study findings.
Intraocular pressure over the clinical range of blood pressure: Blue Mountains Eye Study findings.
复制标题
DOI：
10.1016/j.ajo.2004.12.088
复制
发表时间：
2005-07-01
影响因子：
4.2
通讯作者：
Rochtchina, E
中科院分区：
文献类型：
--
作者：
Mitchell, P;Lee, AJ;Rochtchina, E
目的：在不使用青光眼药物的老年有晶状体眼人群中，量化血压(BP)和眼压(IOP)在临床范围内的关系。设计：横断面人群，基于研究的方法：测量坐位和平视眼压，并用回归模型评估其关系。结果：双眼平均眼压从收缩压14.3 mm Hg线性增加到17.7 mm Hg(收缩压200 mm Hg)，在此范围内漂移3.4 mm Hg。平均眼压也从舒张期BP<；70的15.2 mm Hg增加到舒张期BP>；=120的18.4 mm Hg，变化相似。在年龄和多变量调整眼压后，或排除未确诊的青光眼病例后，眼压没有变化。结论：在临床血压水平上，眼压线性增加3 mm是明显的；这种变化比大多数其他系统和眼睛参数的变化更大。
PURPOSE: To quantify the relation of blood pressure (BP) and intraocular pressure (IOP) across the clinical range of BP in an older phakic population not using glaucoma medications.DESIGN: Cross-sectional population,based studyMETHODS: Seated BP and applanation IOP were measured, and their relation was assessed in regression models.RESULTS: Mean IOP of the two eyes increased linearly from 14.3 mm Hg for systolic BP < 110 mm Hg to 17.7 mm Hg for systolic BP 200 mm Hg, a 3.4-mm Hg excursion over this range. Mean IOP also increased from 15.2 mm Hg for diastolic BP < 70 to 18.4 mm Hg for diastolic BP >= 120, a similar variance. There were no changes after age and multivariate adjustments for IOP or after excluding undiagnosed glaucoma cases.CONCLUSION: A 3-mm linear IOP increase over the clinical spectrum of BP levels was evident; this variance is greater than with most other systemic and ocular parameters.