Apoptosis: Bcl-5-related proteins get connected

Apoptosis: Bcl-5-related proteins get connected
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DOI:
10.1016/s0960-9822(06)00136-9
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发表时间:
1997-05-01
期刊:
影响因子:
9.2
通讯作者:
Jacobson, MD
Jacobson, MD
中科院分区:
生物学1区
文献类型:
--
作者:
Jacobson, MD

文献摘要

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BCL-2家族蛋白是细胞程序性死亡的关键细胞内调节因子。最近的几项发现展示了这些蛋白质如何与控制和执行细胞死亡程序的分子机制相互作用,以及它们本身如何受到细胞外生存信号的调节。
Bcl-2 family proteins are key intracellular regulators of programmed cell death. Several recent discoveries demonstrate how these proteins interact with the molecular machinery that controls and executes the cell-death programme, and how they can themselves be regulated by extracellular survival signals.