Iodine Status of the U.S. Population, National Health and Nutrition Examination Survey, 2005-2006 and 2007-2008

Iodine Status of the U.S. Population, National Health and Nutrition Examination Survey, 2005-2006 and 2007-2008
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DOI:
10.1089/thy.2010.0077
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发表时间:
2011-04-01
期刊:
影响因子:
6.6
通讯作者:
Wang, Richard Y.
Wang, Richard Y.
中科院分区:
医学1区
文献类型:
--
作者:
Caldwell, Kathleen L.;Makhmudov, Amir;Wang, Richard Y.

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背景:本报告介绍了 2005-2006 年和 2007-2008 年美国普通人群的尿碘 (UI) 浓度。这些结果是自国家健康和营养检查调查 (NHANES) III (1988-1994) 以来对人口进行的第四次和第五次评估,当时人口的中位 UI 浓度较 NHANES I (1971-1974) 有所下降。 方法:在 2005-2006 年和 2007-2008 年期间,每年选择大约 5000 名参与者参加 NHANES。参与者接受了采访和检查。 UI 浓度是在 2005 年至 2006 年期间对 2649 名 6 岁及以上参与者的随机三分之一子样本以及 2007 年至 2008 年所有参与者中进行测量的。这些尿碘浓度代表了美国普通人群的年龄、性别和种族/民族。 结果:(i) 2005-2006 年和 2007-2008 年美国普通人群的中位 UI 浓度分别为 164 μg/L(95% 置信区间 [CI] 154-174)和 164 μg/L(95% CI) 154-173),分别。此外,UI 浓度 = 200 μg/L 的人口比例在儿童和 70 岁以上人群中似乎高于其他年龄组。 (ii) 两次调查中,6-11岁儿童UI浓度中位数≥200μg/L,其中约5%的儿童UI浓度>50μg/L。 (iii) 2005-2008 年期间调查的所有孕妇(样本量 184)的 UI 浓度中位数为 125 μg/L(95% CI 86-198),该组中 56.9%+/- 7.9% 的 UI 浓度为
Background: This report presents urinary iodine (UI) concentrations for the general U. S. population during 2005-2006 and 2007-2008. These findings are the fourth and fifth assessments of the population since National Health and Nutrition Examination Survey (NHANES) III (1988-1994), when the median UI concentration for the population decreased from NHANES I (1971-1974).Methods: During 2005-2006 and 2007-2008,similar to 5000 participants per year were selected to participate in NHANES. The participants were interviewed and examined. UI concentration was measured on a random one third sub-sample of 2649 participants, aged 6 years and older in 2005-2006, and in all participants in 2007-2008. These urine iodine concentrations are representative of the general U. S. population by age, sex, and race/ethnicity.Results: (i) The median UI concentrations for the general U. S. population in 2005-2006 and 2007-2008 were 164 mu g/L (95% confidence interval [CI] 154-174) and 164 mu g/L (95% CI 154-173), respectively. Also, the proportions of the population with a UI concentration of = 200 mu g/L appeared to be higher in children and persons >= 70 years than in other age groups. (ii) In both surveys, children aged 6-11 years had median UI concentrations of >= 200 mu g/L, and about 5% of them had a UI concentration of >50 mu g/L. (iii) All pregnant women (sample size 184) surveyed during 2005-2008 had a median UI concentration of 125 mu g/L (95% CI 86-198), and 56.9%+/- 7.9% of this group had a UI concentration of