An overview of the 1999 US Public Health Service/Infectious Diseases Society of America guidelines for preventing opportunistic infections in human immunodeficiency virus-infected persons
An overview of the 1999 US Public Health Service/Infectious Diseases Society of America guidelines for preventing opportunistic infections in human immunodeficiency virus-infected persons
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DOI：
10.1086/313844
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发表时间：
2000-04-01
影响因子：
11.8
通讯作者：
Watts, H
中科院分区：
文献类型：
--
作者：
Kaplan, JE;Masur, H;Watts, H
1999年美国公共卫生服务(USPHS)/美国传染病学会(IDSA)在本期《临床传染病》[1]上发表的《预防HIV感染者机会性感染(OIS)指南》为预防美国HIV感染者最常见的机会性感染提供了具体的建议[2]。这篇文章综合了这些建议，并为卫生保健提供者提供了一种有组织的方法来预防感染艾滋病毒的患者发生OIS。我们认识到，通过建立高效抗逆转录病毒疗法(HAART)来保存或重建免疫功能，现在可以为患有晚期HIV疾病的人提供最有效的OIS保护，包括许多没有特定预防措施的OIS[3，4]。然而，HAART仅对那些能够获得治疗、愿意接受治疗、能够坚持治疗并实现病毒抑制的人有效。本文旨在指导提供者优先考虑各种可用的预防措施，包括HAART和特定的OI预防。与USPHS/IDSA指南[1]一样，本文侧重于美国的艾滋病毒相关护理，但也应适用于世界其他工业化地区。
1999 US Public Health Service (USPHS)/Infectious Diseases Society of America (IDSA) Guidelines for Preventing Opportunistic Infections (OIs) in Persons Infected with HIV, published in this issue of Clinical Infectious Diseases [1], provide diseasespecific recommendations for the prevention of the most common serious OIs in HIV-infected persons in the United States [2]. This article synthesizes these recommendations and offers health care providers an organized approach for preventing OIs in patients infected with HIV. We recognize that preservation or reconstitution of immune function by instituting highly active antiretroviral therapy (HAART) can now provide the most potent protection against OIs in persons with advanced HIV disease, including many OIs for which specific prevention measures are not available [3, 4]. However, HAART is effective only for persons who have access to therapy, who are willing to accept therapy, who are able to adhere to it, and in whom viral suppression is achieved.This article is intended to guide the provider in prioritizing the various prevention measures available, including both HAART and specific OI prevention. As with the USPHS/IDSA guidelines [1], this article focuses on HIV-related care in the United States but should be applicable to other industrialized areas of the world.