2D Au Nanosphere Arrays/PVA-PBA-Modified-Hydrogel Composite Film for Glucose Detection with Strong Diffraction Intensity and Linear Response
2D Au Nanosphere Arrays/PVA-PBA-Modified-Hydrogel Composite Film for Glucose Detection with Strong Diffraction Intensity and Linear Response
复制标题
用于葡萄糖检测的二维金纳米球阵列/PVA-PBA改性水凝胶复合膜，具有强衍射强度和线性响应
DOI：
10.3390/nano9020140
复制
发表时间：
2019-02-01
期刊：
影响因子：
5.3
通讯作者：
Zhang, Honghua
中科院分区：
文献类型：
--
作者：
Li, Wenjuan;Xiang, Junhuai;Zhang, Honghua
报道了一种新型葡萄糖传感器，它由二维金纳米球阵列和葡萄糖响应性水凝胶膜组成。由于金纳米球阵列的强衍射强度，该传感器在石英片上呈现出强烈的衍射信号和明显的衍射颜色。因此，无需高反射镜，通过衍射波长和衍射颜色的变化即可检测葡萄糖。此外，通过引入聚乙烯醇（PVA）交联苯硼酸（PBA）修饰的水凝胶膜，在高离子强度条件下，二维金纳米球阵列/水凝胶复合膜的衍射波长向同一方向移动。特别是当葡萄糖浓度从0 mM增加到20 mM时，它呈现出近乎线性的红移。而且，这种葡萄糖传感器具有良好的重现性。近乎线性的响应和良好的重现性对提高这种葡萄糖传感器的实际应用非常有帮助。
A novel glucose sensor was reported that consisted of two-dimensional (2D) Au nanosphere arrays and glucose-responsive hydrogel film. This sensor exhibited an intense diffraction signal and an obvious diffraction color on a quartz slide due to the strong diffraction intensity of the Au nanosphere arrays. Thus, glucose was detected via the variation of diffraction wavelength and diffraction color, without a high reflective mirror. In addition, by introducing poly(vinyl alcohol) (PVA) to crosslink the phenylboronic acid (PBA)-modified hydrogel film, the diffraction wavelength of the 2D Au nanosphere arrays/hydrogel composite film shifted in the same direction in high ionic strength condition. In particular, it showed a nearly linear red-shift when the glucose concentration increased from 0 mM to 20 mM. Moreover, this glucose sensor displayed good reproducibility. The nearly linear response and good reproducibility were highly helpful for improving practical application of this glucose sensor.