Effects of estradiol-17β on gonadal sex differentiation in two species of salmonids, the masu salmon, Oncorhynchus masou, and the chum salmon, O. keta
Effects of estradiol-17β on gonadal sex differentiation in two species of salmonids, the masu salmon, Oncorhynchus masou, and the chum salmon, O. keta
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雌二醇-17β 对两种鲑鱼（马苏鲑鱼 Oncorhynchus masou 和鲑鱼 O. keta）性腺性别分化的影响
DOI：
10.1016/0044-8486(84)90012-7
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发表时间：
1984
期刊：
影响因子：
4.5
通讯作者：
Masaru Nakamura
中科院分区：
文献类型：
--
作者：
Masaru Nakamura
研究了雌激素处理对两种鲑类性腺雌性化诱导的影响。凯塔）。从孵化后5天开始，将马苏鲑鱼鱼苗浸入含有不同浓度（0.25-200 μg/l水）的雌二醇-17 β（E2）的水中18天。用0.5-5 μg/l的E_2处理组中的大多数鱼的卵巢发育和结构与同龄对照鱼相似，但每个处理组中有1 - 2条鱼在1年后出现了间性性腺。用0.5和1 μg/l的E_2处理6-20日龄的大麻哈鱼22-29天后，其精巢出现部分雌性化，由此得出结论：大麻哈鱼性腺对雌激素的敏感期可能发生在性腺性别分化期的5 ~ 22日龄。在大麻哈鱼中，即使在睾丸分化后，雄性生殖细胞对雌激素的敏感性仍然保持不变。
The effects of estrogen treatment on the induction of gonadal feminization were investigated in two species of salmonids, masu (Oncorhynchus masou) and chum salmon (O. keta). For 18 days, masu salmon fry were immersed in water containing estradiol-17β (E2) at various concentrations (0.25–200 μg/l water) starting from 5 days after hatching. Most fish in the groups treated with 0.5–5 μg/l had ovaries which were similar in development and structure to those of control fish of the same age, although one or two fish in each of the treated groups had intersexual gonads after 1 year.Chum salmon fry at various stages of gonadal sex differentiation were reared in water containing E2at various concentrations (0.5–2 μg/l water) for varying durations. Using 6–20-day-old fish, partial feminization was observed in their testes after treatment with 0.5 and 1 μg/l E2for 22–29 days.From these results, it is concluded that in the masu salmon, the sensitive period of the gonads to estrogen may occur from 5 to 22 days of age during the period of observed gonadal sex differentiation. In the chum salmon, the sensitivity of germ cells to estrogen in genetic males was maintained even after testicular differentiation.